BET1 and STX1B

Data Source:
BioGRID (two hybrid)

		BET1	STX1B
Description		Bet1 golgi vesicular membrane trafficking protein	syntaxin 1B
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Trans Cisterna Golgi Membrane Endoplasmic Reticulum Membrane Membrane Transport Vesicle Integral Component Of Golgi Membrane SNARE Complex Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane	Nucleus Microtubule Organizing Center Spindle Cytosol Plasma Membrane Synaptic Vesicle Endomembrane System Membrane Integral Component Of Membrane Axon SNARE Complex Neuromuscular Junction Presynaptic Active Zone Membrane
	Molecular Function	SNAP Receptor Activity Protein Binding	SNARE Binding Signaling Receptor Binding SNAP Receptor Activity Protein Binding Protein Kinase Binding Protein Domain Specific Binding
	Biological Process	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Protein Transport COPII Vesicle Coating Vesicle Fusion With Golgi Apparatus	Positive Regulation Of Neurotransmitter Secretion Intracellular Protein Transport Exocytosis Vesicle Docking Involved In Exocytosis Vesicle Fusion Regulation Of Gene Expression Regulation Of Synaptic Vesicle Priming Negative Regulation Of Neuron Projection Development Synaptic Vesicle Docking Regulation Of Exocytosis Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Vesicle Docking Calcium Ion-regulated Exocytosis Of Neurotransmitter Regulation Of Synaptic Activity Spontaneous Neurotransmitter Secretion Exocytic Insertion Of Neurotransmitter Receptor To Postsynaptic Membrane Negative Regulation Of Synaptic Vesicle Recycling Positive Regulation Of Spontaneous Neurotransmitter Secretion Negative Regulation Of Macropinocytosis Positive Regulation Of Excitatory Postsynaptic Potential
Pathways		COPII-mediated vesicle transport COPI-mediated anterograde transport	Toxicity of botulinum toxin type C (botC) LGI-ADAM interactions
Drugs
Diseases
GWAS		Aging ( 22773346) Asparaginase hypersensitivity in acute lymphoblastic leukemia ( 25987655) BRCA1/2-negative high-risk breast cancer ( 30323354) Obesity-related traits ( 23251661) World class endurance athleticism ( 26824906)	Adult body size ( 32376654) Body mass index ( 31453325) Body mass index variance ( 31453325) Dementia with Lewy bodies ( 29263008) Hip circumference ( 31453325) Hip circumference variance ( 31453325) Juvenile myoclonic epilepsy ( 30531953) Low density lipoprotein cholesterol levels ( 32154731) Parkinson's disease ( 25064009 32201043) Psoriasis ( 25574825) Response to metformin (IC50) ( 28173075) Waist circumference ( 31453325) Waist circumference variance ( 31453325)
Interacting Genes		52 interacting genes: ADORA2A ANKS6 AQP6 ASGR2 ASZ1 BCL2L13 CD74 CD79A CGRRF1 CISD2 CLDN7 CLEC10A CRB3 CREB3L1 CYB561 CYBC1 ELOVL4 ERGIC3 FAM174A FAM209A FAM210B FAM9B GOSR2 GPR152 GPX8 JAGN1 KASH5 KCNJ6 LYPD5 MAGEA6 MFF MGST3 NAPB PTGES REEP4 RETREG3 SLC26A6 SLC7A14 SNTG2 SSMEM1 STX1A STX1B STX2 STX4 STX5 TMCO5A TMEM237 TMEM35A TMEM52B TMEM80 TMX2 USHBP1	29 interacting genes: ABHD16A ACBD5 AQP6 BET1 EBP ERGIC3 FAM161B FAM209A FAM81A FBXO28 FGA GJA8 GPR152 KCNN4 MMGT1 NAPB SNAP23 SNAP29 SNAP47 STX2 STX4 STXBP1 TMEM167B TXLNA UBE2I UNC13B VAMP1 VAMP2 VAMP5
Entrez ID		10282	112755
HPRD ID		16107	18126
Ensembl ID		ENSG00000105829	ENSG00000099365
Uniprot IDs		O15155 Q53XK0	P61266
PDB IDs		3EGX
Enriched GO Terms of Interacting Partners?
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