POP7 and RPP38

Data Source:
HPRD (in vivo)

		POP7	RPP38
Description		POP7 homolog, ribonuclease P/MRP subunit	ribonuclease P/MRP subunit p38
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GO Annotations	Cellular Component	Ribonuclease MRP Complex Nucleus Nucleoplasm Nucleolus Cytoplasm Multimeric Ribonuclease P Complex Intracellular Membrane-bounded Organelle	Fibrillar Center Nucleoplasm Nucleolus Multimeric Ribonuclease P Complex
	Molecular Function	RNA Binding Ribonuclease P Activity Protein Binding Ribonuclease P RNA Binding	Ribonuclease P Activity Protein Binding Ribonuclease P RNA Binding
	Biological Process	TRNA 5'-leader Removal RRNA Processing TRNA Processing RNA Phosphodiester Bond Hydrolysis, Endonucleolytic	TRNA 5'-leader Removal RRNA Processing RNA Phosphodiester Bond Hydrolysis, Endonucleolytic
Pathways		tRNA processing in the nucleus	tRNA processing in the nucleus Major pathway of rRNA processing in the nucleolus and cytosol
Drugs
Diseases
GWAS		Hematocrit ( 32888494) Hemoglobin ( 32888494) Hemoglobin concentration ( 27863252) Low density lipoprotein cholesterol levels ( 32154731) Medication use (thyroid preparations) ( 31015401) Pursuit maintenance gain in psychotic disorders ( 29064472) Red blood cell count ( 32888494 27863252) Schizophrenia ( 30285260)	Clozapine-induced agranulocytosis ( 25187353) Response to cognitive-behavioural therapy in anxiety disorder ( 31123309)
Interacting Genes		9 interacting genes: APP C9orf72 HSPB1 LAGE3 RPP25 RPP25L RPP38 RPP40 SMN1	9 interacting genes: POP1 POP4 POP7 PTEN RPP14 RPP21 RPP25 RPP30 RPP40
Entrez ID		10248	10557
HPRD ID		09357	09360
Ensembl ID		ENSG00000172336	ENSG00000152464
Uniprot IDs		O75817	P78345
PDB IDs		6AHR 6AHU 6CWX	6AHR 6AHU
Enriched GO Terms of Interacting Partners?
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