GPHN and MITD1

Data Source:
BioGRID (two hybrid)

		GPHN	MITD1
Description		gephyrin	microtubule interacting and trafficking domain containing 1
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GO Annotations	Cellular Component	Cytoplasm Cytosol Cytoskeleton Plasma Membrane Postsynaptic Density Dendrite Postsynaptic Membrane Synaptic Membrane Anchored Component Of Synaptic Membrane Postsynaptic Specialization Postsynaptic Specialization Membrane	Extrinsic Component Of Membrane Midbody Late Endosome Membrane Intracellular Membrane-bounded Organelle Extracellular Exosome
	Molecular Function	Protein Binding ATP Binding Nitrate Reductase Activity Identical Protein Binding Molybdopterin Cofactor Binding Metal Ion Binding Molybdopterin Adenylyltransferase Activity Molybdopterin Molybdotransferase Activity	Protein Binding Protein Domain Specific Binding Phosphatidylinositol Binding Identical Protein Binding
	Biological Process	Mo-molybdopterin Cofactor Biosynthetic Process Establishment Of Synaptic Specificity At Neuromuscular Junction Response To Metal Ion Molybdenum Incorporation Into Molybdenum-molybdopterin Complex Molybdopterin Cofactor Biosynthetic Process Glycine Receptor Clustering Gamma-aminobutyric Acid Receptor Clustering Postsynaptic Neurotransmitter Receptor Diffusion Trapping	Mitotic Cytokinesis Negative Regulation Of Protein Binding Viral Budding Via Host ESCRT Complex Midbody Abscission Multivesicular Body Sorting Pathway
Pathways		Molybdenum cofactor biosynthesis
Drugs		Formic acid Imidazole Propanoic acid
Diseases		Hyperekplexia
GWAS		Depression (quantitative trait) ( 23290196) Pneumococcal meningitis ( 31092817) Tandem gait ( 26219847) Waist circumference adjusted for body mass index ( 28552196)	Bipolar disorder ( 21926972)
Interacting Genes		15 interacting genes: ACADVL ARHGEF9 DYNLL1 DYNLL2 ENAH GABARAP GLRB KHDRBS1 MITD1 MTOR PFN1 PIN1 PSMA1 SPATS1 TUBA4A	15 interacting genes: ATF7 CARD10 CHMP1A CHMP1B CHMP2A CHMP5 GPHN KANK2 MCPH1 NTAQ1 RTN3 TRIM14 TTC33 ZFYVE19 ZNF655
Entrez ID		10243	129531
HPRD ID		04893	14044
Ensembl ID		ENSG00000171723	ENSG00000158411
Uniprot IDs		Q9NQX3	Q8WV92
PDB IDs		1JLJ	2YMB 4A5X 4A5Z
Enriched GO Terms of Interacting Partners?
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