MITD1 and CHMP2A

Data Source:
BioGRID (two hybrid, affinity chromatography technology)
HPRD (two hybrid, in vivo)

		MITD1	CHMP2A
Description		microtubule interacting and trafficking domain containing 1	charged multivesicular body protein 2A
Image			No pdb structure
GO Annotations	Cellular Component	Extrinsic Component Of Membrane Midbody Late Endosome Membrane Intracellular Membrane-bounded Organelle Extracellular Exosome	Chromatin ESCRT III Complex Nuclear Envelope Multivesicular Body Cytosol Membrane Membrane Coat Late Endosome Membrane Extracellular Exosome
	Molecular Function	Protein Binding Protein Domain Specific Binding Phosphatidylinositol Binding Identical Protein Binding	Protein Binding Protein Domain Specific Binding Phosphatidylcholine Binding
	Biological Process	Mitotic Cytokinesis Negative Regulation Of Protein Binding Viral Budding Via Host ESCRT Complex Midbody Abscission Multivesicular Body Sorting Pathway	Nucleus Organization Mitotic Metaphase Plate Congression Membrane Invagination Exit From Mitosis Regulation Of Centrosome Duplication Protein Transport Endosomal Transport Macroautophagy Viral Life Cycle Nuclear Envelope Reassembly Endosome Transport Via Multivesicular Body Sorting Pathway Multivesicular Body Assembly Viral Budding Via Host ESCRT Complex Establishment Of Protein Localization Late Endosome To Vacuole Transport Regulation Of Viral Process Protein Polymerization Protein Homooligomerization Negative Regulation Of Cell Death Midbody Abscission Regulation Of Mitotic Spindle Assembly Positive Regulation Of Viral Release From Host Cell Positive Regulation Of Exosomal Secretion Negative Regulation Of Centriole Elongation ESCRT III Complex Disassembly
Pathways			Budding and maturation of HIV virion Macroautophagy Lysosome Vesicle Biogenesis Endosomal Sorting Complex Required For Transport (ESCRT) HCMV Late Events Late endosomal microautophagy Sealing of the nuclear envelope (NE) by ESCRT-III Translation of Replicase and Assembly of the Replication Transcription Complex Translation of Replicase and Assembly of the Replication Transcription Complex
Drugs
Diseases
GWAS		Bipolar disorder ( 21926972)	Mean corpuscular hemoglobin ( 32888494)
Interacting Genes		15 interacting genes: ATF7 CARD10 CHMP1A CHMP1B CHMP2A CHMP5 GPHN KANK2 MCPH1 NTAQ1 RTN3 TRIM14 TTC33 ZFYVE19 ZNF655	13 interacting genes: CHMP3 DOCK8 E2F4 EIF2B5 MITD1 NOL4 STAMBP TGFB3 UFD1 USP54 USP8 VPS4A VPS4B
Entrez ID		129531	27243
HPRD ID		14044	12520
Ensembl ID		ENSG00000158411	ENSG00000130724
Uniprot IDs		Q8WV92	A0A024R4S0 O43633
PDB IDs		2YMB 4A5X 4A5Z
Enriched GO Terms of Interacting Partners?
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