ARPC3 and RPS4X

Data Source:
BioGRID (two hybrid)

		ARPC3	RPS4X
Description		actin related protein 2/3 complex subunit 3	ribosomal protein S4 X-linked
Image
GO Annotations	Cellular Component	Nucleus Cytosol Arp2/3 Protein Complex Focal Adhesion Actin Cytoskeleton Membrane Lamellipodium Filamentous Actin Site Of Double-strand Break Growth Cone Leading Edge Extracellular Exosome	Nucleoplasm Cytosol Ribosome Polysome Focal Adhesion Small Ribosomal Subunit Membrane Cytosolic Small Ribosomal Subunit Cytoplasmic Ribonucleoprotein Granule Synapse Extracellular Exosome Ribonucleoprotein Complex
	Molecular Function	Structural Constituent Of Cytoskeleton Protein Binding Actin Filament Binding	RNA Binding Structural Constituent Of Ribosome Protein Binding RRNA Binding
	Biological Process	Arp2/3 Complex-mediated Actin Nucleation Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Ephrin Receptor Signaling Pathway Membrane Organization Actin Polymerization-dependent Cell Motility Cellular Response To Nerve Growth Factor Stimulus	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Translation Translational Initiation SRP-dependent Cotranslational Protein Targeting To Membrane Multicellular Organism Development Positive Regulation Of Cell Population Proliferation Viral Transcription Response To Ethanol Positive Regulation Of Translation
Pathways		Regulation of actin dynamics for phagocytic cup formation Regulation of actin dynamics for phagocytic cup formation EPHB-mediated forward signaling RHO GTPases Activate WASPs and WAVEs RHO GTPases Activate WASPs and WAVEs Clathrin-mediated endocytosis FCGR3A-mediated phagocytosis FCGR3A-mediated phagocytosis	L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis Major pathway of rRNA processing in the nucleolus and cytosol Translation initiation complex formation Formation of a pool of free 40S subunits Formation of the ternary complex, and subsequently, the 43S complex Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs		N-[2-(2-methyl-1H-indol-3-yl)ethyl]thiophene-2-carboxamide (2S)-2-(3-bromophenyl)-3-(5-chloro-2-hydroxyphenyl)-1,3-thiazolidin-4-one
Diseases
GWAS		Automobile speeding propensity ( 30643258) Bipolar disorder ( 31043756) Femoral neck bone mineral density ( 30172743)
Interacting Genes		30 interacting genes: ACTR3 ARAP1 ARPC4 BAG6 CCR10 CDKN2B CETP DUSP29 EFTUD2 FAM9A GOLGA2 HOXA3 LATS1 LGALS4 LTA4H MAPK6 NRIP1 OTUD5 POU2F1 PRMT1 RBBP8NL RETREG3 RPS4X SYBU TARS3 THNSL2 WAS WASF2 WASL ZNF576	13 interacting genes: ARPC3 CAMK2D CTBP2 DUX4 HNRNPH3 MCM2 PTEN RPS15 RPS7 RPS8 SUMO2 TRIM55 TRIM63
Entrez ID		10094	6191
HPRD ID		09175	02427
Ensembl ID		ENSG00000111229	ENSG00000198034
Uniprot IDs		O15145	B2R491 P62701
PDB IDs		6UHC 6YW6 6YW7	4UG0 4V6X 5A2Q 5LKS 5OA3 5T2C 5VYC 6EK0 6FEC 6G18 6G4S 6G4W 6G51 6G53 6G5H 6G5I 6IP5 6IP6 6IP8 6OLE 6OLF 6OLI 6OM0 6OM7 6QZP 6XA1 6Y0G 6Y2L 6Y57 6YBW 6Z6L 6Z6M 6Z6N 6ZLW 6ZM7 6ZME 6ZMI 6ZMO 6ZMT 6ZMW 6ZN5 6ZOJ 6ZOK 6ZON 6ZP4 6ZVH 6ZVJ 7A09 7K5I
Enriched GO Terms of Interacting Partners?
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