ARPC3 and SYBU

Data Source:
BioGRID (two hybrid)

		ARPC3	SYBU
Description		actin related protein 2/3 complex subunit 3	syntabulin
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol Arp2/3 Protein Complex Focal Adhesion Actin Cytoskeleton Membrane Lamellipodium Filamentous Actin Site Of Double-strand Break Growth Cone Leading Edge Extracellular Exosome	Golgi Membrane Microtubule Cytoplasmic Microtubule Integral Component Of Membrane Cytoplasmic Vesicle Vesicle Intracellular Membrane-bounded Organelle Axon Cytoplasm
	Molecular Function	Structural Constituent Of Cytoskeleton Protein Binding Actin Filament Binding	Protein Binding Microtubule Binding Syntaxin-1 Binding Kinesin Binding
	Biological Process	Arp2/3 Complex-mediated Actin Nucleation Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Ephrin Receptor Signaling Pathway Membrane Organization Actin Polymerization-dependent Cell Motility Cellular Response To Nerve Growth Factor Stimulus	Axonal Transport Of Mitochondrion Synapse Maturation
Pathways		Regulation of actin dynamics for phagocytic cup formation Regulation of actin dynamics for phagocytic cup formation EPHB-mediated forward signaling RHO GTPases Activate WASPs and WAVEs RHO GTPases Activate WASPs and WAVEs Clathrin-mediated endocytosis FCGR3A-mediated phagocytosis FCGR3A-mediated phagocytosis
Drugs		N-[2-(2-methyl-1H-indol-3-yl)ethyl]thiophene-2-carboxamide (2S)-2-(3-bromophenyl)-3-(5-chloro-2-hydroxyphenyl)-1,3-thiazolidin-4-one
Diseases
GWAS		Automobile speeding propensity ( 30643258) Bipolar disorder ( 31043756) Femoral neck bone mineral density ( 30172743)	Ankle-brachial index ( 31388106)
Interacting Genes		30 interacting genes: ACTR3 ARAP1 ARPC4 BAG6 CCR10 CDKN2B CETP DUSP29 EFTUD2 FAM9A GOLGA2 HOXA3 LATS1 LGALS4 LTA4H MAPK6 NRIP1 OTUD5 POU2F1 PRMT1 RBBP8NL RETREG3 RPS4X SYBU TARS3 THNSL2 WAS WASF2 WASL ZNF576	7 interacting genes: ARPC3 ATXN1 CLASP1 DISC1 EXOC1 KIF5B RPL29
Entrez ID		10094	55638
HPRD ID		09175	07902
Ensembl ID		ENSG00000111229	ENSG00000147642
Uniprot IDs		O15145	B7Z4D2 Q9NX95
PDB IDs		6UHC 6YW6 6YW7
Enriched GO Terms of Interacting Partners?
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