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IRF2
Description
interferon regulatory factor 2
Image
No pdb structure
GO Annotations
Cellular Component
Chromatin
Nucleus
Nucleoplasm
Cytosol
Focal Adhesion
Molecular Function
RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
DNA Binding
DNA-binding Transcription Factor Activity
Protein Binding
Sequence-specific Double-stranded DNA Binding
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Immune System Process
Regulation Of Transcription, DNA-templated
Regulation Of Transcription By RNA Polymerase II
Blood Coagulation
Cell Population Proliferation
Positive Regulation Of Transcription By RNA Polymerase II
Defense Response To Virus
Interferon-gamma-mediated Signaling Pathway
Type I Interferon Signaling Pathway
Pathways
Interferon gamma signaling
Interferon alpha/beta signaling
Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS
Acute kidney injury in critical illness (
27576016
)
Adverse response to drug (
30420678
)
Chronic lymphocytic leukemia (
28165464
)
Hippocampal volume in Alzheimer's disease dementia (
29274321
)
Lewy body disease (
25188341
)
Night sleep phenotypes (
27126917
)
Nonsyndromic cleft lip (
31609978
)
Interacting Genes
23 interacting genes:
APP
ATG7
BRD7
CSNK2A1
EP300
FKBP7
FOXK1
HMGB1
HMGN1
IRF2BP1
IRF2BP2
IRF8
KAT2A
KAT2B
MDM2
NFKB1
PPP3CB
PRKACA
RELA
SPI1
STAT1
TRIM55
TRIM63
Entrez ID
3660
HPRD ID
00962
Ensembl ID
ENSG00000168310
Uniprot IDs
P14316
PDB IDs
Enriched GO Terms of Interacting Partners
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