ECE2 and SYNE4

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid)

		ECE2	SYNE4
Description		endothelin converting enzyme 2	spectrin repeat containing nuclear envelope family member 4
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Plasma Membrane Integral Component Of Membrane Transport Vesicle Membrane Cytoplasmic Vesicle Membrane	Integral Component Of Nuclear Outer Membrane Meiotic Nuclear Membrane Microtubule Tethering Complex
	Molecular Function	Metalloendopeptidase Activity Methyltransferase Activity Metal Ion Binding	Protein Binding
	Biological Process	G Protein-coupled Receptor Signaling Pathway Cell-cell Signaling Protein Processing Peptide Hormone Processing Methylation	Establishment Of Epithelial Cell Apical/basal Polarity
Pathways		Peptide ligand-binding receptors
Drugs
Diseases
GWAS		Body mass index ( 29273807) Daytime nap ( 33568662) Major depressive disorder ( 22472876) Menarche (age at onset) ( 21102462)
Interacting Genes		6 interacting genes: CASP10 CD53 CD86 MTNR1A SYNE4 UBC	57 interacting genes: ABT1 ADIPOQ BRICD5 C3orf52 CD47 CEP19 CLDN19 CLDN7 CLDN8 CLEC7A CMTM5 CSGALNACT2 CSNK2B CXCL9 DEFB121 ECE2 EDDM3B EMP1 ENTPD3 FAM241B FATE1 GADD45A GSK3B IGFBP5 ITM2B KLHL12 KLRG1 KTN1 MALL MARCHF2 NAGK OCLN OLFM4 OSTCP1 PAQR5 PLPP6 RIPPLY2 RPS6KA6 SEC22A SEC23B SENP2 SFTPC SLN SMCO4 TCEA2 TMEM115 TMEM140 TMEM147 TMEM182 TMEM248 TMPRSS4 TRIM69 TSPAN15 VTI1B WDR62 ZNF250 ZNF648
Entrez ID		9718	163183
HPRD ID		09931	08776
Ensembl ID		ENSG00000145194	ENSG00000181392
Uniprot IDs		P0DPD6 P0DPD8	Q8N205
PDB IDs			6R16 6WMD
Enriched GO Terms of Interacting Partners?
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