ECE2 and CD53

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		ECE2	CD53
Description		endothelin converting enzyme 2	CD53 molecule
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Plasma Membrane Integral Component Of Membrane Transport Vesicle Membrane Cytoplasmic Vesicle Membrane	Immunological Synapse Plasma Membrane Integral Component Of Plasma Membrane Cell-cell Junction Cell Surface Specific Granule Membrane Extracellular Exosome Tertiary Granule Membrane
	Molecular Function	Metalloendopeptidase Activity Methyltransferase Activity Metal Ion Binding	Protein Binding Identical Protein Binding
	Biological Process	G Protein-coupled Receptor Signaling Pathway Cell-cell Signaling Protein Processing Peptide Hormone Processing Methylation	Signal Transduction Positive Regulation Of Myoblast Fusion
Pathways		Peptide ligand-binding receptors	Neutrophil degranulation
Drugs
Diseases
GWAS		Body mass index ( 29273807) Daytime nap ( 33568662) Major depressive disorder ( 22472876) Menarche (age at onset) ( 21102462)	Cytomegalovirus antibody response ( 21993531) Obesity-related traits ( 23251661)
Interacting Genes		6 interacting genes: CASP10 CD53 CD86 MTNR1A SYNE4 UBC	80 interacting genes: AIG1 APOD ARL13B ASGR2 ATP6V0C BCL2L13 BIK BTN2A2 C1QL4 CD2 CD302 CD37 CD4 CD9 CLCN7 CLDN19 CLDN7 CLEC7A CNIH1 CNIH2 COL4A5 CREB3L1 CTXN3 CXCL16 CYBC1 ECE2 EFNA5 EMP1 ERG28 FAM209A GET1 GGT1 GIMAP5 GJA8 GPR108 GPR152 GPX8 IFITM3 IGFBP5 IL2 IL4 KIR3DL3 LAT LHFPL5 LPAR3 LSMEM1 MAL MS4A3 MUC1 NKG7 PLN PLP2 PMP22 PSCA RPRM SAR1A SERTM1 SLC35A1 SLC7A14 SMAGP SMIM3 SNORC ST6GAL2 STRIT1 STX2 TMEM128 TMEM140 TMEM218 TMEM229B TMEM237 TMEM60 TMEM86B TMEM97 TRAM1L1 TRARG1 TSPO2 UBIAD1 UPK1B VAMP5 VSTM1
Entrez ID		9718	963
HPRD ID		09931	01054
Ensembl ID		ENSG00000145194	ENSG00000143119
Uniprot IDs		P0DPD6 P0DPD8	B4DQB5 P19397
PDB IDs			6WVG
Enriched GO Terms of Interacting Partners?
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