SYNE4 and CSGALNACT2

Number of citations of the paper that reports this interaction (PubMedID 28514442)
406

Data Source:
BioGRID (affinity chromatography technology, two hybrid)

		SYNE4	CSGALNACT2
Description		spectrin repeat containing nuclear envelope family member 4	chondroitin sulfate N-acetylgalactosaminyltransferase 2
Image			No pdb structure
GO Annotations	Cellular Component	Integral Component Of Nuclear Outer Membrane Meiotic Nuclear Membrane Microtubule Tethering Complex	Golgi Membrane Membrane Integral Component Of Golgi Membrane Golgi Cisterna Membrane
	Molecular Function	Protein Binding	Protein Binding Acetylgalactosaminyltransferase Activity Metal Ion Binding Glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase Activity Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase Activity
	Biological Process	Establishment Of Epithelial Cell Apical/basal Polarity	Proteoglycan Biosynthetic Process Chondroitin Sulfate Biosynthetic Process Chondroitin Sulfate Proteoglycan Biosynthetic Process Dermatan Sulfate Proteoglycan Biosynthetic Process Dermatan Sulfate Proteoglycan Biosynthetic Process, Polysaccharide Chain Biosynthetic Process Chondroitin Sulfate Proteoglycan Biosynthetic Process, Polysaccharide Chain Biosynthetic Process
Pathways			Chondroitin sulfate biosynthesis
Drugs
Diseases
GWAS			Blood protein levels ( 30072576 29875488) Central corneal thickness ( 32528159) Hip circumference adjusted for BMI ( 34021172) Hirschsprung disease ( 25310821) Multiple sclerosis ( 24076602)
Interacting Genes		57 interacting genes: ABT1 ADIPOQ BRICD5 C3orf52 CD47 CEP19 CLDN19 CLDN7 CLDN8 CLEC7A CMTM5 CSGALNACT2 CSNK2B CXCL9 DEFB121 ECE2 EDDM3B EMP1 ENTPD3 FAM241B FATE1 GADD45A GSK3B IGFBP5 ITM2B KLHL12 KLRG1 KTN1 MALL MARCHF2 NAGK OCLN OLFM4 OSTCP1 PAQR5 PLPP6 RIPPLY2 RPS6KA6 SEC22A SEC23B SENP2 SFTPC SLN SMCO4 TCEA2 TMEM115 TMEM140 TMEM147 TMEM182 TMEM248 TMPRSS4 TRIM69 TSPAN15 VTI1B WDR62 ZNF250 ZNF648	20 interacting genes: ARL13B ATP1B4 BSND CLDN2 CREB3L1 CYB5R3 FCGR2A GPR152 HSD17B11 LMNA MFSD14B MUC1 RETREG3 SLC35E3 SSMEM1 SYNE4 SYT1 TMEM143 TMEM52B UBE2I
Entrez ID		163183	55454
HPRD ID		08776	11348
Ensembl ID		ENSG00000181392	ENSG00000169826
Uniprot IDs		Q8N205	A0A0S2Z5F5 A0A0S2Z5F9 A0A0S2Z5K4 Q8N6G5
PDB IDs		6R16 6WMD
Enriched GO Terms of Interacting Partners?
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