MDC1 and UIMC1

  • Number of citations of the paper that reports this interaction (PubMedID 29656893)
  • 112
  • Data Source:
  • BioGRID (proximity labelling technology, pull down, pull down, affinity chromatography technology)

MDC1

UIMC1

Description mediator of DNA damage checkpoint 1 ubiquitin interaction motif containing 1
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Activated partial thromboplastin time ( 22703881)
  • Menarche and menopause (age at onset) ( 19448621)
  • Menopause (age at onset) ( 22267201 26414677 29773799)
  • Uterine fibroids ( 31649266)
  • Waist circumference adjusted for body mass index ( 34021172)
  • Waist-to-hip ratio adjusted for BMI ( 26426971)
  • Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971)
  • Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes 41 interacting genes: ANAPC1 ATM BARD1 BDKRB1 BRCA1 CASP3 CENPC CHEK2 COPS5 CREBBP CSNK2A1 DTX2 EP300 GATA4 H2AX HDAC10 HDAC8 HINFP NBN NCL NSD2 PIAS1 PIAS4 PRIM1 PTEN RAD50 RAD51 RNF8 SMC1A SRPK2 SUMO2 TNKS2 TP53 TP53BP1 UIMC1 USP13 USP15 USP28 VAMP5 WRN ZNF251 23 interacting genes: ABRAXAS1 ATP8A2 BRCC3 CEP57 CREBBP DVL2 DYNLT3 ECPAS ESR1 FANCG H2AC20 INO80B MDC1 NR6A1 RAD23A SKIL SUMO2 TP53 UBB UBC USP13 WBP2 ZMYM3
Entrez ID 9656 51720
HPRD ID 16252 11482
Ensembl ID ENSG00000137337 ENSG00000087206
Uniprot IDs A0A1U9XBC1 A1Z5I9 Q14676 A0A024R7R0 Q96RL1
PDB IDs 2ADO 2AZM 2ETX 3K05 3UEO 3UMZ 3UN0 3UNM 3UNN 3UOT 2MKF 2MKG 2N9E 2RR9
Enriched GO Terms of Interacting Partners?
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