CD48 and ACKR1

		CD48	ACKR1
Description		CD48 molecule	atypical chemokine receptor 1 (Duffy blood group)
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GO Annotations	Cellular Component	Plasma Membrane External Side Of Plasma Membrane Membrane Anchored Component Of Membrane Intrinsic Component Of Plasma Membrane Membrane Raft Extracellular Exosome	Early Endosome Plasma Membrane Integral Component Of Membrane Recycling Endosome
	Molecular Function	Antigen Binding Protein Binding Signaling Receptor Activity	Transmembrane Signaling Receptor Activity G Protein-coupled Receptor Activity C-C Chemokine Binding Signaling Receptor Activity
	Biological Process	Regulation Of Adaptive Immune Response Defense Response T Cell Activation	Defense Response Inflammatory Response G Protein-coupled Receptor Signaling Pathway Regulation Of Chemokine Production Chemokine-mediated Signaling Pathway
Pathways		Cell surface interactions at the vascular wall	Peptide ligand-binding receptors
Drugs
Diseases
GWAS		Blood protein levels ( 30072576 29875488) Inflammatory bowel disease ( 23128233) Itch intensity from mosquito bite ( 28199695) Multiple sclerosis ( 31604244) Venous thromboembolism adjusted for sickle cell variant rs77121243-T ( 28203683)	Eotaxin levels ( 27989323) Growth-regulated protein alpha levels ( 27989323) Midgestational total 25-hydroxyvitamin D levels (fetal genetic effect) ( 32047095) Monocyte chemoattractant protein-1 levels ( 27989323 31217265) Neutrophil level response to clozapine in treatment-resistant schizophrenia ( 30647433)
Interacting Genes		20 interacting genes: ACKR1 BRIX1 C1orf68 CD2 CD244 CD247 DIO1 E2F2 EEF1D EFNA1 EFNA3 FYN GNAI3 IL18R1 IL18RAP LCK LY9 MAST2 OAZ3 P4HA1	10 interacting genes: CCL17 CCL2 CCL5 CCL7 CCL8 CD48 CXCL1 CXCL5 CXCL8 MTNR1B
Entrez ID		962	2532
HPRD ID		00177	00192
Ensembl ID		ENSG00000117091	ENSG00000213088
Uniprot IDs		A0A087X1S7 P09326	Q16570 Q5Y7A1 Q5Y7A2
PDB IDs		2EDO	4NUU 4NUV
Enriched GO Terms of Interacting Partners?
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