CD48 and CD244

Number of citations of the paper that reports this interaction (PubMedID 9834056)
39

Data Source:
HPRD (in vivo, in vitro)

		CD48	CD244
Description		CD48 molecule	CD244 molecule
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane External Side Of Plasma Membrane Membrane Anchored Component Of Membrane Intrinsic Component Of Plasma Membrane Membrane Raft Extracellular Exosome	Plasma Membrane External Side Of Plasma Membrane Integral Component Of Membrane
	Molecular Function	Antigen Binding Protein Binding Signaling Receptor Activity	Protein Binding Signaling Receptor Activity MHC Class I Protein Binding
	Biological Process	Regulation Of Adaptive Immune Response Defense Response T Cell Activation	Adaptive Immune Response Natural Killer Cell Activation Involved In Immune Response Signal Transduction Positive Regulation Of Interferon-gamma Production Positive Regulation Of Interleukin-8 Production Innate Immune Response Positive Regulation Of Inositol Phosphate Biosynthetic Process Positive Regulation Of Granzyme B Production
Pathways		Cell surface interactions at the vascular wall	Cell surface interactions at the vascular wall
Drugs
Diseases
GWAS		Blood protein levels ( 30072576 29875488) Inflammatory bowel disease ( 23128233) Itch intensity from mosquito bite ( 28199695) Multiple sclerosis ( 31604244) Venous thromboembolism adjusted for sickle cell variant rs77121243-T ( 28203683)	Blood protein levels ( 28240269) Crohn's disease ( 21102463) Inflammatory bowel disease ( 23128233) Lymphocyte percentage of white cells ( 32888494) Neutrophil percentage of white cells ( 32888494) White blood cell count ( 32888494)
Interacting Genes		20 interacting genes: ACKR1 BRIX1 C1orf68 CD2 CD244 CD247 DIO1 E2F2 EEF1D EFNA1 EFNA3 FYN GNAI3 IL18R1 IL18RAP LCK LY9 MAST2 OAZ3 P4HA1	11 interacting genes: ACO2 ARHGEF7 CD247 CD48 LAT OLFML2B PCGF1 PDGFRA SH2D1A SH2D1B TOMM40L
Entrez ID		962	51744
HPRD ID		00177	16121
Ensembl ID		ENSG00000117091	ENSG00000122223
Uniprot IDs		A0A087X1S7 P09326	Q9BZW8
PDB IDs		2EDO
Enriched GO Terms of Interacting Partners?
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