ACKR1 and CD48

		ACKR1	CD48
Description		atypical chemokine receptor 1 (Duffy blood group)	CD48 molecule
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GO Annotations	Cellular Component	Early Endosome Plasma Membrane Integral Component Of Membrane Recycling Endosome	Plasma Membrane External Side Of Plasma Membrane Membrane Anchored Component Of Membrane Intrinsic Component Of Plasma Membrane Membrane Raft Extracellular Exosome
	Molecular Function	Transmembrane Signaling Receptor Activity G Protein-coupled Receptor Activity C-C Chemokine Binding Signaling Receptor Activity	Antigen Binding Protein Binding Signaling Receptor Activity
	Biological Process	Defense Response Inflammatory Response G Protein-coupled Receptor Signaling Pathway Regulation Of Chemokine Production Chemokine-mediated Signaling Pathway	Regulation Of Adaptive Immune Response Defense Response T Cell Activation
Pathways		Peptide ligand-binding receptors	Cell surface interactions at the vascular wall
Drugs
Diseases
GWAS		Eotaxin levels ( 27989323) Growth-regulated protein alpha levels ( 27989323) Midgestational total 25-hydroxyvitamin D levels (fetal genetic effect) ( 32047095) Monocyte chemoattractant protein-1 levels ( 27989323 31217265) Neutrophil level response to clozapine in treatment-resistant schizophrenia ( 30647433)	Blood protein levels ( 30072576 29875488) Inflammatory bowel disease ( 23128233) Itch intensity from mosquito bite ( 28199695) Multiple sclerosis ( 31604244) Venous thromboembolism adjusted for sickle cell variant rs77121243-T ( 28203683)
Interacting Genes		10 interacting genes: CCL17 CCL2 CCL5 CCL7 CCL8 CD48 CXCL1 CXCL5 CXCL8 MTNR1B	20 interacting genes: ACKR1 BRIX1 C1orf68 CD2 CD244 CD247 DIO1 E2F2 EEF1D EFNA1 EFNA3 FYN GNAI3 IL18R1 IL18RAP LCK LY9 MAST2 OAZ3 P4HA1
Entrez ID		2532	962
HPRD ID		00192	00177
Ensembl ID		ENSG00000213088	ENSG00000117091
Uniprot IDs		Q16570 Q5Y7A1 Q5Y7A2	A0A087X1S7 P09326
PDB IDs		4NUU 4NUV	2EDO
Enriched GO Terms of Interacting Partners?
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