CD48 and P4HA1

		CD48	P4HA1
Description		CD48 molecule	prolyl 4-hydroxylase subunit alpha 1
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GO Annotations	Cellular Component	Plasma Membrane External Side Of Plasma Membrane Membrane Anchored Component Of Membrane Intrinsic Component Of Plasma Membrane Membrane Raft Extracellular Exosome	Mitochondrion Endoplasmic Reticulum Endoplasmic Reticulum Lumen Membrane Procollagen-proline 4-dioxygenase Complex Intracellular Membrane-bounded Organelle
	Molecular Function	Antigen Binding Protein Binding Signaling Receptor Activity	Procollagen-proline 4-dioxygenase Activity Iron Ion Binding Protein Binding L-ascorbic Acid Binding Identical Protein Binding
	Biological Process	Regulation Of Adaptive Immune Response Defense Response T Cell Activation	Peptidyl-proline Hydroxylation To 4-hydroxy-L-proline Collagen Fibril Organization
Pathways		Cell surface interactions at the vascular wall	Collagen biosynthesis and modifying enzymes
Drugs			Ascorbic acid Proline Hydralazine
Diseases
GWAS		Blood protein levels ( 30072576 29875488) Inflammatory bowel disease ( 23128233) Itch intensity from mosquito bite ( 28199695) Multiple sclerosis ( 31604244) Venous thromboembolism adjusted for sickle cell variant rs77121243-T ( 28203683)	Alanine aminotransferase levels ( 33547301)
Interacting Genes		20 interacting genes: ACKR1 BRIX1 C1orf68 CD2 CD244 CD247 DIO1 E2F2 EEF1D EFNA1 EFNA3 FYN GNAI3 IL18R1 IL18RAP LCK LY9 MAST2 OAZ3 P4HA1	4 interacting genes: CD48 MLF2 OGT SUMO2
Entrez ID		962	5033
HPRD ID		00177	08901
Ensembl ID		ENSG00000117091	ENSG00000122884
Uniprot IDs		A0A087X1S7 P09326	P13674 Q5VSQ6
PDB IDs		2EDO	1TJC 2V5F 2YQ8 4BT8 4BT9 4BTA 4BTB
Enriched GO Terms of Interacting Partners?
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