SCARB1 and PXN

SCARB1

PXN

Description scavenger receptor class B member 1 paxillin
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Alzheimer's disease or HDL levels (pleiotropy) ( 30805717)
  • Apolipoprotein A1 levels ( 32203549)
  • Apolipoprotein B levels ( 32203549)
  • Coronary artery disease ( 29212778 33020668)
  • Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975)
  • Gut microbiota relative abundance (Ruminococcus belonging to family Lachnospiraceae) ( 33208821)
  • HDL cholesterol ( 24097068 30275531 25961943 20686565)
  • HDL cholesterol levels ( 32203549 28334899 30698716)
  • HDL cholesterol levels in current drinkers ( 30698716)
  • HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
  • HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
  • High density lipoprotein cholesterol levels ( 29403010 33339817 31217584)
  • Hip circumference adjusted for BMI ( 34021172)
  • Hip index ( 34021172)
  • LDL cholesterol levels ( 32203549)
  • Lipoprotein phospholipase A2 activity in cardiovascular disease ( 28753643)
  • Lipoprotein-associated phospholipase A2 activity and mass ( 23118302 20442857)
  • Low density lipoprotein cholesterol levels ( 32154731)
  • Lung function (FEV1) ( 30061609)
  • Mean corpuscular hemoglobin ( 32888494)
  • Mean corpuscular volume ( 32888494)
  • Mean spheric corpuscular volume ( 32888494)
  • Medication use (HMG CoA reductase inhibitors) ( 31015401)
  • Metabolite levels (lipoprotein measures) ( 27005778)
  • Monocyte count ( 32888494)
  • Monocyte percentage of white cells ( 32888494)
  • Myocardial infarction ( 33532862)
  • Renal cell carcinoma ( 21131975)
  • Response to cyclophosphamide in systemic lupus erythematosus with lupus nephritis ( 26980576)
  • Serum metabolite levels ( 33031748)
  • Total bilirubin levels ( 29403010)
  • Total cholesterol levels ( 29403010 33339817)
  • Triglyceride levels ( 32203549)
  • Triglycerides ( 30275531)
  • Vitamin E levels ( 21729881)
  • Waist-hip index ( 34021172)
  • Waist-to-hip ratio adjusted for BMI ( 34021172)
  • Bipolar disorder ( 31043756)
  • Left ventricle wall thickness ( 33495596)
  • Left ventricular end-systolic volume ( 33495596)
  • Left ventricular mass to end-diastolic volume ratio ( 33495596)
  • Mean spheric corpuscular volume ( 32888494)
  • Platelet count ( 29403010)
Interacting Genes 18 interacting genes: APOA1 APOA2 APOE CASP10 DENR GGA1 GPR35 GTF2H3 KRTAP10-9 KRTAP5-9 LTB4R2 PDZK1 PEX5 POLE PRL PXN SNAP23 SRSF9 90 interacting genes: ABL1 ACO1 AHCY AR ARHGEF7 ASAP1 ASAP2 BCAR1 BCL2 BLK CASP3 CEACAM1 CLTC CREB3L2 CRK CRKL CSK DGUOK DPY30 EPHB1 FYN GART GIT1 GIT2 GRB2 GSK3A GSK3B GSN HDAC6 ILK IMPDH2 ITGA4 ITGA6 ITGA9 ITGAV ITGB1 ITGB3 LCK LIMK1 LMO1 LMO3 MAPK1 MAPK3 MAPK8 MATK NCK1 NEDD9 NF2 PABPC1 PAK1 PAK3 PARVA PCM1 PDPK1 PKD1 PLEKHH2 PLEKHN1 POLR1D PPP2CA PPP2R5C PTEN PTK2 PTK2B PTPN11 PTPN12 PTPRH RASA1 REPS2 RHOU RNF5 SCARB1 SDC4 SELE SH3RF1 SORBS1 SRC SYK TCEANC TGM2 TLN1 TRIM15 TRIP6 TUBA1B TUBA3C TUBA8 TUBG1 TUBG2 VCL WHRN YES1
Entrez ID 949 5829
HPRD ID 03024 03937
Ensembl ID ENSG00000073060 ENSG00000089159
Uniprot IDs A0A024RBS4 Q8WTV0 A0A140VJQ8 P49023
PDB IDs 1KKY 1KL0 1OW6 1OW7 1OW8 2K2R 2O9V 2VZD 2VZG 2VZI 3GM1 3PY7 3RQE 3RQF 3RQG 3U3F 4EDN 4R32 4XGZ 4XH2 5UWH 6IUI 6PW8 6U4M 6U4N
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
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