SCARB1 and APOA1

  • Number of citations of the paper that reports this interaction (PubMedID 1076467)
  • 0
  • Data Source:
  • HPRD (in vivo)

SCARB1

APOA1

Description scavenger receptor class B member 1 apolipoprotein A1
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Alzheimer's disease or HDL levels (pleiotropy) ( 30805717)
  • Apolipoprotein A1 levels ( 32203549)
  • Apolipoprotein B levels ( 32203549)
  • Coronary artery disease ( 29212778 33020668)
  • Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975)
  • Gut microbiota relative abundance (Ruminococcus belonging to family Lachnospiraceae) ( 33208821)
  • HDL cholesterol ( 24097068 30275531 25961943 20686565)
  • HDL cholesterol levels ( 32203549 28334899 30698716)
  • HDL cholesterol levels in current drinkers ( 30698716)
  • HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
  • HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
  • High density lipoprotein cholesterol levels ( 29403010 33339817 31217584)
  • Hip circumference adjusted for BMI ( 34021172)
  • Hip index ( 34021172)
  • LDL cholesterol levels ( 32203549)
  • Lipoprotein phospholipase A2 activity in cardiovascular disease ( 28753643)
  • Lipoprotein-associated phospholipase A2 activity and mass ( 23118302 20442857)
  • Low density lipoprotein cholesterol levels ( 32154731)
  • Lung function (FEV1) ( 30061609)
  • Mean corpuscular hemoglobin ( 32888494)
  • Mean corpuscular volume ( 32888494)
  • Mean spheric corpuscular volume ( 32888494)
  • Medication use (HMG CoA reductase inhibitors) ( 31015401)
  • Metabolite levels (lipoprotein measures) ( 27005778)
  • Monocyte count ( 32888494)
  • Monocyte percentage of white cells ( 32888494)
  • Myocardial infarction ( 33532862)
  • Renal cell carcinoma ( 21131975)
  • Response to cyclophosphamide in systemic lupus erythematosus with lupus nephritis ( 26980576)
  • Serum metabolite levels ( 33031748)
  • Total bilirubin levels ( 29403010)
  • Total cholesterol levels ( 29403010 33339817)
  • Triglyceride levels ( 32203549)
  • Triglycerides ( 30275531)
  • Vitamin E levels ( 21729881)
  • Waist-hip index ( 34021172)
  • Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes 18 interacting genes: APOA1 APOA2 APOE CASP10 DENR GGA1 GPR35 GTF2H3 KRTAP10-9 KRTAP5-9 LTB4R2 PDZK1 PEX5 POLE PRL PXN SNAP23 SRSF9 37 interacting genes: ABCA1 ABCA13 AKT2 APOB APOC1 APOF APOL1 APP ATP5F1B BRAP CETP CFHR1 CLEC4G CMTM5 FBLN1 GPLD1 HPR HSP90AA1 JAK3 LBP LCAT MAP7D1 NAXE NDRG1 PCMT1 PDE1A PLTP POLR1H PON1 SAA2 SCARB1 SPP1 TNFRSF10C TOMM20 TREM2 TTR VKORC1
Entrez ID 949 335
HPRD ID 03024 02517
Ensembl ID ENSG00000073060 ENSG00000118137
Uniprot IDs A0A024RBS4 Q8WTV0 A0A024R3E3 P02647
PDB IDs 1AV1 1GW3 1GW4 1ODP 1ODQ 1ODR 2MSC 2MSD 2MSE 2N5E 3K2S 3R2P 4V6M 6CC9 6CCH 6CCX 6CLZ 6CM1 6PTS 6PTW 6W4E 6W4F 7KJR
Enriched GO Terms of Interacting Partners?
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