SCARB1 and GTF2H3

SCARB1

GTF2H3

Description scavenger receptor class B member 1 general transcription factor IIH subunit 3
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Alzheimer's disease or HDL levels (pleiotropy) ( 30805717)
  • Apolipoprotein A1 levels ( 32203549)
  • Apolipoprotein B levels ( 32203549)
  • Coronary artery disease ( 29212778 33020668)
  • Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975)
  • Gut microbiota relative abundance (Ruminococcus belonging to family Lachnospiraceae) ( 33208821)
  • HDL cholesterol ( 24097068 30275531 25961943 20686565)
  • HDL cholesterol levels ( 32203549 28334899 30698716)
  • HDL cholesterol levels in current drinkers ( 30698716)
  • HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
  • HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
  • High density lipoprotein cholesterol levels ( 29403010 33339817 31217584)
  • Hip circumference adjusted for BMI ( 34021172)
  • Hip index ( 34021172)
  • LDL cholesterol levels ( 32203549)
  • Lipoprotein phospholipase A2 activity in cardiovascular disease ( 28753643)
  • Lipoprotein-associated phospholipase A2 activity and mass ( 23118302 20442857)
  • Low density lipoprotein cholesterol levels ( 32154731)
  • Lung function (FEV1) ( 30061609)
  • Mean corpuscular hemoglobin ( 32888494)
  • Mean corpuscular volume ( 32888494)
  • Mean spheric corpuscular volume ( 32888494)
  • Medication use (HMG CoA reductase inhibitors) ( 31015401)
  • Metabolite levels (lipoprotein measures) ( 27005778)
  • Monocyte count ( 32888494)
  • Monocyte percentage of white cells ( 32888494)
  • Myocardial infarction ( 33532862)
  • Renal cell carcinoma ( 21131975)
  • Response to cyclophosphamide in systemic lupus erythematosus with lupus nephritis ( 26980576)
  • Serum metabolite levels ( 33031748)
  • Total bilirubin levels ( 29403010)
  • Total cholesterol levels ( 29403010 33339817)
  • Triglyceride levels ( 32203549)
  • Triglycerides ( 30275531)
  • Vitamin E levels ( 21729881)
  • Waist-hip index ( 34021172)
  • Waist-to-hip ratio adjusted for BMI ( 34021172)
  • Gut microbiota relative abundance (Prevotella) ( 33208821)
  • Late-onset Alzheimer's disease ( 27770636)
  • Waist-to-hip ratio adjusted for BMI ( 26426971)
  • Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971)
  • Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes 18 interacting genes: APOA1 APOA2 APOE CASP10 DENR GGA1 GPR35 GTF2H3 KRTAP10-9 KRTAP5-9 LTB4R2 PDZK1 PEX5 POLE PRL PXN SNAP23 SRSF9 9 interacting genes: AR CDK7 ERCC2 ERCC3 GTF2E1 GTF2H2 GTF2H4 SCARB1 XBP1P1
Entrez ID 949 2967
HPRD ID 03024 07531
Ensembl ID ENSG00000073060 ENSG00000111358
Uniprot IDs A0A024RBS4 Q8WTV0 A0A087WYD5 Q13889
PDB IDs 5IVW 5IY6 5IY7 5IY8 5IY9 5O85 5OF4 6NMI 6O9L 6O9M 6RO4
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?