RAB33A and ATG16L1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid, affinity chromatography technology)

		RAB33A	ATG16L1
Description		RAB33A, member RAS oncogene family	autophagy related 16 like 1
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endosome Golgi Apparatus Plasma Membrane	Autophagosome Membrane Autophagosome Cytosol Axoneme Phagophore Assembly Site Membrane Vacuole-isolation Membrane Contact Site
	Molecular Function	GTPase Activity Protein Binding GTP Binding	Protein Binding Ubiquitin-like Protein Transferase Activity Identical Protein Binding GTPase Binding
	Biological Process	Antigen Processing And Presentation Rab Protein Signal Transduction	Autophagosome Assembly Positive Regulation Of Autophagy Protein Transport Macroautophagy Protein Localization To Phagophore Assembly Site Negative Stranded Viral RNA Replication Protein Lipidation Involved In Autophagosome Assembly Xenophagy
Pathways		TBC/RABGAPs RAB geranylgeranylation	Macroautophagy Macroautophagy
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756) Height ( 31562340)	Bilirubin levels ( 31801373 31319653 32084209) Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007) Crohn's disease ( 18587394 28067908 20570966 22936669 22412388 17435756 17554300 21102463 23128233) Inflammatory bowel disease ( 28067908) Pediatric autoimmune diseases ( 26301688) Serum alkaline phosphatase levels ( 33547301)
Interacting Genes		15 interacting genes: ARL6IP1 ATG16L1 ATG16L2 CCDC136 KRT31 KRT34 LNX1 LRP2BP PSMF1 RABAC1 RTN3 RTN4 RUFY2 RUFY3 SIAH1	18 interacting genes: APP ATG5 C3 CSNK2A1 CSNK2A2 DEDD2 GAN GIGYF2 NOD1 NOD2 OPTN PLD3 RAB33A RAB33B SCAP SETD7 TRAF3IP3 ZFP36
Entrez ID		9363	55054
HPRD ID		02272	16498
Ensembl ID		ENSG00000134594	ENSG00000085978
Uniprot IDs		Q14088	A0A024R494 A0A024R4B6 Q17RG0 Q53SV2 Q676U5
PDB IDs			4GDK 4GDL 4NAW 4TQ0 5D7G 5NPV 5NPW 5NUV 5ZYX
Enriched GO Terms of Interacting Partners?
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