CHMP4C and TRPC4AP

Number of citations of the paper that reports this interaction (PubMedID 16730941)
66

Data Source:
HPRD (two hybrid)

		CHMP4C	TRPC4AP
Description		charged multivesicular body protein 4C	transient receptor potential cation channel subfamily C member 4 associated protein
Image			No pdb structure
GO Annotations	Cellular Component	ESCRT III Complex Multivesicular Body Cytosol Cytoplasmic Side Of Plasma Membrane Midbody Late Endosome Membrane Flemming Body	Plasma Membrane Cul4A-RING E3 Ubiquitin Ligase Complex Cul4-RING E3 Ubiquitin Ligase Complex
	Molecular Function	Protein Binding Protein Homodimerization Activity	Calcium Channel Activity Protein Binding Phosphatase Binding Ubiquitin Ligase-substrate Adaptor Activity
	Biological Process	Vesicle Budding From Membrane Nucleus Organization Mitotic Metaphase Plate Congression Abscission Regulation Of Centrosome Duplication Protein Transport Macroautophagy Negative Regulation Of Cytokinesis Late Endosome To Vacuole Transport Via Multivesicular Body Sorting Pathway Multivesicular Body Assembly Viral Budding Via Host ESCRT Complex Mitotic Cytokinesis Checkpoint Signaling Viral Budding From Plasma Membrane Midbody Abscission Ubiquitin-independent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Regulation Of Mitotic Spindle Assembly	Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Hair Follicle Maturation Calcium Ion Transmembrane Transport Ubiquitin-dependent Protein Catabolic Process Via The C-end Degron Rule Pathway
Pathways		Budding and maturation of HIV virion Macroautophagy Pyroptosis Endosomal Sorting Complex Required For Transport (ESCRT) HCMV Late Events Late endosomal microautophagy Sealing of the nuclear envelope (NE) by ESCRT-III Translation of Replicase and Assembly of the Replication Transcription Complex Translation of Replicase and Assembly of the Replication Transcription Complex	TRP channels
Drugs
Diseases
GWAS		Epithelial ovarian cancer ( 25581431) Ovarian cancer ( 23535730)	Basal cell carcinoma ( 33549134) Blood protein levels ( 28240269) Fish- and plant-related diet ( 32066663) HDL cholesterol levels ( 32203549) Heel bone mineral density ( 30598549) Hip circumference adjusted for BMI ( 34021172) Prothrombin time ( 22703881) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		10 interacting genes: CC2D1A CHMP4A CHMP4B HMGB3P1 PDCD6IP STAMBP TRPC4AP USP54 USP8 VPS4A	18 interacting genes: CHMP4C CHUK CPNE1 CUL4B EDEM2 IKBKB IKBKG MED26 MTDH PCDH11X PGLYRP4 RIPK1 TAB1 TNFRSF1A TRADD TRAF2 UQCC1 VMP1
Entrez ID		92421	26133
HPRD ID		18135	09238
Ensembl ID		ENSG00000164695	ENSG00000100991
Uniprot IDs		Q96CF2	B4DW48 Q8TEL6
PDB IDs		3C3R 5MK3 5V3R 5WA1
Enriched GO Terms of Interacting Partners?
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