CHMP4C and CC2D1A

Number of citations of the paper that reports this interaction (PubMedID 16730941)
66

Data Source:
HPRD (two hybrid)

		CHMP4C	CC2D1A
Description		charged multivesicular body protein 4C	coiled-coil and C2 domain containing 1A
Image			No pdb structure
GO Annotations	Cellular Component	ESCRT III Complex Multivesicular Body Cytosol Cytoplasmic Side Of Plasma Membrane Midbody Late Endosome Membrane Flemming Body	Fibrillar Center Nucleus Microtubule Organizing Center Cytosol Plasma Membrane Membrane Extracellular Exosome
	Molecular Function	Protein Binding Protein Homodimerization Activity	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Protein Binding Cadherin Binding
	Biological Process	Vesicle Budding From Membrane Nucleus Organization Mitotic Metaphase Plate Congression Abscission Regulation Of Centrosome Duplication Protein Transport Macroautophagy Negative Regulation Of Cytokinesis Late Endosome To Vacuole Transport Via Multivesicular Body Sorting Pathway Multivesicular Body Assembly Viral Budding Via Host ESCRT Complex Mitotic Cytokinesis Checkpoint Signaling Viral Budding From Plasma Membrane Midbody Abscission Ubiquitin-independent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Regulation Of Mitotic Spindle Assembly	Regulation Of Transcription By RNA Polymerase II Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Negative Regulation Of SnRNA Transcription By RNA Polymerase II
Pathways		Budding and maturation of HIV virion Macroautophagy Pyroptosis Endosomal Sorting Complex Required For Transport (ESCRT) HCMV Late Events Late endosomal microautophagy Sealing of the nuclear envelope (NE) by ESCRT-III Translation of Replicase and Assembly of the Replication Transcription Complex Translation of Replicase and Assembly of the Replication Transcription Complex
Drugs
Diseases
GWAS		Epithelial ovarian cancer ( 25581431) Ovarian cancer ( 23535730)
Interacting Genes		10 interacting genes: CC2D1A CHMP4A CHMP4B HMGB3P1 PDCD6IP STAMBP TRPC4AP USP54 USP8 VPS4A	4 interacting genes: CDC37 CHMP4A CHMP4C LRP1
Entrez ID		92421	54862
HPRD ID		18135	08616
Ensembl ID		ENSG00000164695	ENSG00000132024
Uniprot IDs		Q96CF2	Q6P1N0
PDB IDs		3C3R 5MK3 5V3R 5WA1
Enriched GO Terms of Interacting Partners?
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