TRPC4AP and MED26

		TRPC4AP	MED26
Description		transient receptor potential cation channel subfamily C member 4 associated protein	mediator complex subunit 26
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Cul4A-RING E3 Ubiquitin Ligase Complex Cul4-RING E3 Ubiquitin Ligase Complex	Nucleoplasm Mediator Complex Core Mediator Complex
	Molecular Function	Calcium Channel Activity Protein Binding Phosphatase Binding Ubiquitin Ligase-substrate Adaptor Activity	Transcription Coregulator Activity Transcription Coactivator Activity Protein Binding
	Biological Process	Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Hair Follicle Maturation Calcium Ion Transmembrane Transport Ubiquitin-dependent Protein Catabolic Process Via The C-end Degron Rule Pathway	Regulation Of Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Positive Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated
Pathways		TRP channels	PPARA activates gene expression Generic Transcription Pathway Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation
Drugs
Diseases
GWAS		Basal cell carcinoma ( 33549134) Blood protein levels ( 28240269) Fish- and plant-related diet ( 32066663) HDL cholesterol levels ( 32203549) Heel bone mineral density ( 30598549) Hip circumference adjusted for BMI ( 34021172) Prothrombin time ( 22703881) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203)
Interacting Genes		18 interacting genes: CHMP4C CHUK CPNE1 CUL4B EDEM2 IKBKB IKBKG MED26 MTDH PCDH11X PGLYRP4 RIPK1 TAB1 TNFRSF1A TRADD TRAF2 UQCC1 VMP1	10 interacting genes: AURKA CDK8 CTDP1 GDF15 MED12 MED8 MED9 RBP1 SREBF1 TRPC4AP
Entrez ID		26133	9441
HPRD ID		09238	05437
Ensembl ID		ENSG00000100991	ENSG00000105085
Uniprot IDs		B4DW48 Q8TEL6	O95402
PDB IDs			5ODD
Enriched GO Terms of Interacting Partners?
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