CHMP4C and USP54

Number of citations of the paper that reports this interaction (PubMedID 19302785)
8

Data Source:
BioGRID (pull down)

		CHMP4C	USP54
Description		charged multivesicular body protein 4C	ubiquitin specific peptidase 54
Image			No pdb structure
GO Annotations	Cellular Component	ESCRT III Complex Multivesicular Body Cytosol Cytoplasmic Side Of Plasma Membrane Midbody Late Endosome Membrane Flemming Body
	Molecular Function	Protein Binding Protein Homodimerization Activity	Thiol-dependent Deubiquitinase Protein Binding
	Biological Process	Vesicle Budding From Membrane Nucleus Organization Mitotic Metaphase Plate Congression Abscission Regulation Of Centrosome Duplication Protein Transport Macroautophagy Negative Regulation Of Cytokinesis Late Endosome To Vacuole Transport Via Multivesicular Body Sorting Pathway Multivesicular Body Assembly Viral Budding Via Host ESCRT Complex Mitotic Cytokinesis Checkpoint Signaling Viral Budding From Plasma Membrane Midbody Abscission Ubiquitin-independent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Regulation Of Mitotic Spindle Assembly	Protein Deubiquitination
Pathways		Budding and maturation of HIV virion Macroautophagy Pyroptosis Endosomal Sorting Complex Required For Transport (ESCRT) HCMV Late Events Late endosomal microautophagy Sealing of the nuclear envelope (NE) by ESCRT-III Translation of Replicase and Assembly of the Replication Transcription Complex Translation of Replicase and Assembly of the Replication Transcription Complex
Drugs
Diseases
GWAS		Epithelial ovarian cancer ( 25581431) Ovarian cancer ( 23535730)	Childhood ALL/LBL (acute lymphoblastic leukemia/lymphoblastic lymphoma) treatment-related venous thromboembolism ( 32438682) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223)
Interacting Genes		10 interacting genes: CC2D1A CHMP4A CHMP4B HMGB3P1 PDCD6IP STAMBP TRPC4AP USP54 USP8 VPS4A	100 interacting genes: ANKRD11 ANKS1A ARID5B ARMC7 ATN1 ATXN1 ATXN1L ATXN7L2 BFSP2 BHLHE40 CARD10 CCDC13 CCDC24 CCNK CDC23 CDK19 CFAP70 CHCHD2 CHERP CHMP1B CHMP2A CHMP2B CHMP4C COMTD1 CSTF2 CYSRT1 DMRT3 DOK6 DTX2 EIF4E2 EPM2AIP1 EXOC8 FAM124B FAM149B1 FBXO17 FNDC3B FOXI1 FUT11 GCM2 HGS HK1 HNF1B HNRNPF HOXC8 IGFN1 INSC KCTD9 LMO3 LNX1 MED25 MID2 MSS51 MSX2 NUDT22 NXT2 OIP5 OTX1 PCSK5 PHF1 PLA2G6 PLAC8 PLCD1 PLEKHN1 POLR1C PRDM6 PRKAB2 PRR35 QRICH1 RACK1 RAMAC RBPMS2 RHOBTB3 RNF208 SAMD8 SEC24A SHARPIN SHC3 SMARCD1 SMYD1 SNRPB SS18L1 STK16 TBX6 TCEA2 TEKT5 TENT5B TFAP2D TLE5 TNS2 TOLLIP TSEN15 TSSK3 TTC19 TTYH1 UBC USP2 VENTX ZCCHC14 ZNF148 ZNF76
Entrez ID		92421	159195
HPRD ID		18135	15641
Ensembl ID		ENSG00000164695	ENSG00000166348
Uniprot IDs		Q96CF2	B7Z7X1 Q70EL1
PDB IDs		3C3R 5MK3 5V3R 5WA1
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?