SKAP2 and FRK

  • Number of citations of the paper that reports this interaction (PubMedID 29568343)
  • 2
  • Data Source:
  • BioGRID (protein complementation assay)

SKAP2

FRK

Description src kinase associated phosphoprotein 2 fyn related Src family tyrosine kinase
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007)
  • Chronic venous disease ( 28374850)
  • Disease free survival in colon cancer ( 31811950)
  • Erosive tooth wear (severe vs non-severe) ( 29898447)
  • Erosive tooth wear (severe vs none or mild) ( 29898447)
  • FEV1 ( 30804560)
  • Hip index ( 34021172)
  • Lung function (FVC) ( 30804560)
  • Lymphocyte counts ( 32888494)
  • Lymphocyte percentage of white cells ( 32888494)
  • Macular thickness ( 30535121)
  • Peak expiratory flow ( 30804560)
  • Small cell lung carcinoma ( 28604730)
  • Survival in colon cancer ( 31811950)
  • Systemic lupus erythematosus ( 28714469)
  • Age-related macular degeneration ( 21665990)
  • Alanine aminotransferase levels ( 33547301 34315874)
  • Apolipoprotein A1 levels ( 32203549)
  • Apolipoprotein B levels ( 32203549)
  • Appendicular lean mass ( 28724990)
  • Aspartate aminotransferase levels ( 33547301 34315874)
  • C-reactive protein levels ( 30388399)
  • C-reactive protein levels or LDL-cholesterol levels (pleiotropy) ( 27286809)
  • C-reactive protein levels or total cholesterol levels (pleiotropy) ( 27286809)
  • Cholesterol, total ( 24097068 20686565)
  • Choroid plexus volume ( 31530798)
  • Chronotype ( 30696823)
  • Cognitive decline rate in late mild cognitive impairment ( 26252872)
  • Diastolic blood pressure ( 27841878)
  • Emphysema annual change measurement in smokers (adjusted lung density) ( 31324189)
  • HDL cholesterol levels ( 32203549 30698716)
  • High density lipoprotein cholesterol levels ( 33339817)
  • HOMA-B (corrected for HOMA-IR) ( 30369944)
  • LDL cholesterol ( 24097068 20686565)
  • LDL cholesterol levels ( 32203549 28334899)
  • LDL cholesterol levels in current drinkers ( 30698716)
  • LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
  • LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
  • Longevity ( 30294719)
  • Low density lipoprotein cholesterol levels ( 32154731)
  • Photic sneeze reflex ( 27182965)
  • Refractive error ( 32231278)
  • Serum alkaline phosphatase levels ( 33547301)
  • Total cholesterol levels ( 28334899)
  • Urate levels ( 23263486)
Interacting Genes 20 interacting genes: APP BLK DNAJB6 FAM102A FASLG FGR FRK FYB1 FYN HCK KHDRBS1 LCK LYN NCK2 PRAM1 PTK2B SRC SRMS TGFBR1 YES1 7 interacting genes: BNIP2 EGFR KHDRBS1 PRDM1 RB1 SF3B4 SKAP2
Entrez ID 8935 2444
HPRD ID 05558 05954
Ensembl ID ENSG00000005020 ENSG00000111816
Uniprot IDs B7Z5R3 O75563 P42685
PDB IDs 3OMH
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?