FRK and RB1

  • Number of citations of the paper that reports this interaction (PubMedID 7664264)
  • 15
  • Data Source:
  • BioGRID (pull down, affinity chromatography technology)
  • HPRD (in vivo, in vitro)

FRK

RB1

Description fyn related Src family tyrosine kinase RB transcriptional corepressor 1
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Age-related macular degeneration ( 21665990)
  • Alanine aminotransferase levels ( 33547301 34315874)
  • Apolipoprotein A1 levels ( 32203549)
  • Apolipoprotein B levels ( 32203549)
  • Appendicular lean mass ( 28724990)
  • Aspartate aminotransferase levels ( 33547301 34315874)
  • C-reactive protein levels ( 30388399)
  • C-reactive protein levels or LDL-cholesterol levels (pleiotropy) ( 27286809)
  • C-reactive protein levels or total cholesterol levels (pleiotropy) ( 27286809)
  • Cholesterol, total ( 24097068 20686565)
  • Choroid plexus volume ( 31530798)
  • Chronotype ( 30696823)
  • Cognitive decline rate in late mild cognitive impairment ( 26252872)
  • Diastolic blood pressure ( 27841878)
  • Emphysema annual change measurement in smokers (adjusted lung density) ( 31324189)
  • HDL cholesterol levels ( 32203549 30698716)
  • High density lipoprotein cholesterol levels ( 33339817)
  • HOMA-B (corrected for HOMA-IR) ( 30369944)
  • LDL cholesterol ( 24097068 20686565)
  • LDL cholesterol levels ( 32203549 28334899)
  • LDL cholesterol levels in current drinkers ( 30698716)
  • LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
  • LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
  • Longevity ( 30294719)
  • Low density lipoprotein cholesterol levels ( 32154731)
  • Photic sneeze reflex ( 27182965)
  • Refractive error ( 32231278)
  • Serum alkaline phosphatase levels ( 33547301)
  • Total cholesterol levels ( 28334899)
  • Urate levels ( 23263486)
Interacting Genes 7 interacting genes: BNIP2 EGFR KHDRBS1 PRDM1 RB1 SF3B4 SKAP2 199 interacting genes: AATF ABL1 AHR ANKS1A AR ARID3B ATF2 BAAT BAG1 BDP1 BNC2 BRCA1 BRF1 CASP10 CASP2 CASP3 CASP6 CASP7 CASP8 CASP9 CBX1 CBX4 CCDC180 CCNA1 CCNA2 CCNB1 CCNC CCND1 CCND2 CCND3 CCNE1 CCNT2 CDADC1 CDC27 CDK1 CDK14 CDK2 CDK3 CDK4 CDK5 CDK6 CDK9 CDKN1A CDKN1C CEBPA CEBPB CEBPD CEBPE CHEK1 CHN2 CLNK CNTN3 CORO2A COX17 CREG1 CRYBA4 CSK CTBP1 CTSV CUX1 DGKZ DNMT1 DVL1 DYRK1A E2F1 E2F2 E2F3 E2F4 E4F1 EID1 ELF1 ENC1 EP300 ESD FANCC FBP1 FBP2 FOS FRK GALNT12 GTF3C2 HBP1 HDAC1 HDAC3 HIF1A HMGA2 HMGB1 HSPA8 ID2 INS IRF3 JUN KAT2B KAT5 KDM4A KDM5A KDM5B KMT5C L3MBTL1 LEF1 LIN54 LIN9 LMNA LRCH1 MAPK1 MAPK14 MAPK3 MAPK9 MCM7 MDM2 MDM4 MNAT1 MNDA MORF4L1 MORF4L2 MRPS18B MTRF1 MYC MYOD1 NCOA6 NDC80 NEFM ORC1 PA2G4 PAX2 PAX5 PAX6 PCDHB5 PELP1 PHB PIK3R1 PIK3R3 PLA2G12A PML POLA1 PPARG PPIA PPP1CA PPP1CB PPP1CC PPP1R26 PRDM2 PRKCB PRKRA PRMT2 PSMD10 PURA RABGAP1L RACK1 RAF1 RASA1 RBAK RBBP4 RBBP5 RBBP6 RBBP7 RBBP8 RBBP9 RING1 RINT1 RNF123 RNF40 RUNX2 SERPINB2 SHC1 SKP2 SMARCA4 SMARCB1 SMYD2 SNAPC1 SNAPC3 SNW1 SP1 SP3 SPI1 SPIB STAT3 STX17 SUV39H1 TAF1 TASOR TBP TFAP2A TGM2 THOC1 TMPO TOP2A TP53 TRAP1 TRIM27 TRIP11 TRMO UBE2I UBTF USP4 USP7 VDR XPA ZBTB16
Entrez ID 2444 5925
HPRD ID 05954 01574
Ensembl ID ENSG00000111816 ENSG00000139687
Uniprot IDs P42685 A0A024RDV3 P06400
PDB IDs 1AD6 1GH6 1GUX 1H25 1N4M 1O9K 1PJM 2AZE 2QDJ 2R7G 3N5U 3POM 4CRI 4ELJ 4ELL
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
Tagcloud (Intersection) ?