SKAP2 and BLK

  • Number of citations of the paper that reports this interaction (PubMedID 29568343)
  • 2
  • Data Source:
  • BioGRID (protein complementation assay)

SKAP2

BLK

Description src kinase associated phosphoprotein 2 BLK proto-oncogene, Src family tyrosine kinase
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007)
  • Chronic venous disease ( 28374850)
  • Disease free survival in colon cancer ( 31811950)
  • Erosive tooth wear (severe vs non-severe) ( 29898447)
  • Erosive tooth wear (severe vs none or mild) ( 29898447)
  • FEV1 ( 30804560)
  • Hip index ( 34021172)
  • Lung function (FVC) ( 30804560)
  • Lymphocyte counts ( 32888494)
  • Lymphocyte percentage of white cells ( 32888494)
  • Macular thickness ( 30535121)
  • Peak expiratory flow ( 30804560)
  • Small cell lung carcinoma ( 28604730)
  • Survival in colon cancer ( 31811950)
  • Systemic lupus erythematosus ( 28714469)
Interacting Genes 20 interacting genes: APP BLK DNAJB6 FAM102A FASLG FGR FRK FYB1 FYN HCK KHDRBS1 LCK LYN NCK2 PRAM1 PTK2B SRC SRMS TGFBR1 YES1 56 interacting genes: AR BCAS2 BCL2 BCL2L1 BCR BIRC2 CBL CCDC33 CD79A CD79B CRKL CTR9 EFS EGFR EGR3 ERBB2 ERBB3 ERBB4 FAM167A FBXO7 FCGR2A FCGR2B FLACC1 FXR1 FXR2 GAB1 GRB10 HSF2BP IKZF3 JAKMIP1 KIT MET MID2 MTMR9 PICK1 PIK3R1 PIK3R3 PLCG2 PXN SH2D1B SKAP2 SLA SOCS1 SOCS3 SPAG11B SSBP3 STAP2 STAT3 TDP2 TFAP2C UBE3A ZBTB32 ZBTB42 ZBTB8A ZMAT1 ZNF774
Entrez ID 8935 640
HPRD ID 05558 01866
Ensembl ID ENSG00000005020 ENSG00000136573
Uniprot IDs B7Z5R3 O75563 E9PJX5 P51451 Q05D26
PDB IDs 3OMH
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
Tagcloud (Intersection) ?