SNX4 and ATP6V0A1

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		SNX4	ATP6V0A1
Description		sorting nexin 4	ATPase H+ transporting V0 subunit a1
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytoplasmic Dynein Complex Plasma Membrane Membrane SNARE Complex Early Endosome Membrane Protein-containing Complex	Vacuolar Proton-transporting V-type ATPase, V0 Domain Lysosomal Membrane Golgi Apparatus Cytosol Plasma Membrane Endosome Membrane Integral Component Of Membrane Vacuolar Proton-transporting V-type ATPase Complex Nuclear Speck Secretory Granule Membrane Phagocytic Vesicle Membrane Melanosome Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm Extracellular Exosome Ficolin-1-rich Granule Membrane
	Molecular Function	Epidermal Growth Factor Receptor Binding Insulin Receptor Binding Protein Binding Phosphatidylinositol Binding Transferrin Receptor Binding Leptin Receptor Binding	Protein Binding Proton Transmembrane Transporter Activity ATPase Binding
	Biological Process	Protein Transport Endocytic Recycling Positive Regulation Of Histamine Secretion By Mast Cell	Vacuolar Acidification Regulation Of Macroautophagy Toxin Transport Proton Transmembrane Transport
Pathways			ROS and RNS production in phagocytes Neutrophil degranulation Insulin receptor recycling Transferrin endocytosis and recycling Ion channel transport
Drugs			Tiludronic acid
Diseases
GWAS		Adult body size ( 32376654) Estimated glomerular filtration rate in non-diabetics ( 31451708) Major depressive disorder x sex interaction ( 34099189) Urate levels ( 31578528)	Asthma ( 32296059) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Ulcerative colitis ( 28067908) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		19 interacting genes: AGK ARL6IP1 ATP6V0A1 BIN1 DGAT2L6 EGFR HIVEP1 INSR LEPR MAGEA6 OGT PDGFRA PDGFRB PTPN5 SH3GLB1 SNX2 SNX6 SNX7 SUPT5H	7 interacting genes: ABLIM2 CLIC1 CYTH2 HRH1 SEH1L SNX4 ZNF267
Entrez ID		8723	535
HPRD ID		09334	01886
Ensembl ID		ENSG00000114520	ENSG00000033627
Uniprot IDs		O95219	Q53ET5 Q53X12 Q5CZH6 Q93050
PDB IDs			6WLW 6WM2 6WM3 6WM4
Enriched GO Terms of Interacting Partners?
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