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ATP6V0A1

Description ATPase H+ transporting V0 subunit a1
Image
GO Annotations Cellular Component
  • Vacuolar Proton-transporting V-type ATPase, V0 Domain
  • Lysosomal Membrane
  • Golgi Apparatus
  • Cytosol
  • Plasma Membrane
  • Endosome Membrane
  • Integral Component Of Membrane
  • Vacuolar Proton-transporting V-type ATPase Complex
  • Nuclear Speck
  • Secretory Granule Membrane
  • Phagocytic Vesicle Membrane
  • Melanosome
  • Intracellular Membrane-bounded Organelle
  • Perinuclear Region Of Cytoplasm
  • Extracellular Exosome
  • Ficolin-1-rich Granule Membrane
Molecular Function
  • Protein Binding
  • Proton Transmembrane Transporter Activity
  • ATPase Binding
Biological Process
  • Vacuolar Acidification
  • Regulation Of Macroautophagy
  • Toxin Transport
  • Proton Transmembrane Transport
Pathways
  • ROS and RNS production in phagocytes
  • Neutrophil degranulation
  • Insulin receptor recycling
  • Transferrin endocytosis and recycling
  • Ion channel transport
Drugs
  • Tiludronic acid
Diseases
GWAS
  • Asthma ( 32296059)
  • Crohn's disease ( 28067908)
  • Inflammatory bowel disease ( 28067908)
  • Ulcerative colitis ( 28067908)
  • Waist-hip index ( 34021172)
  • Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes 7 interacting genes: ABLIM2 CLIC1 CYTH2 HRH1 SEH1L SNX4 ZNF267
Entrez ID 535
HPRD ID 01886
Ensembl ID ENSG00000033627
Uniprot IDs Q53ET5 Q53X12 Q5CZH6 Q93050
PDB IDs 6WLW 6WM2 6WM3 6WM4
Enriched GO Terms of Interacting Partners?
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