ATP6V0A1 and CLIC1

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		ATP6V0A1	CLIC1
Description		ATPase H+ transporting V0 subunit a1	chloride intracellular channel 1
Image
GO Annotations	Cellular Component	Vacuolar Proton-transporting V-type ATPase, V0 Domain Lysosomal Membrane Golgi Apparatus Cytosol Plasma Membrane Endosome Membrane Integral Component Of Membrane Vacuolar Proton-transporting V-type ATPase Complex Nuclear Speck Secretory Granule Membrane Phagocytic Vesicle Membrane Melanosome Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm Extracellular Exosome Ficolin-1-rich Granule Membrane	Extracellular Space Nucleus Nuclear Envelope Cytoplasm Mitochondrion Plasma Membrane Brush Border Membrane Nuclear Membrane Vesicle Chloride Channel Complex Perinuclear Region Of Cytoplasm Extracellular Exosome Blood Microparticle
	Molecular Function	Protein Binding Proton Transmembrane Transporter Activity ATPase Binding	Voltage-gated Ion Channel Activity Chloride Channel Activity Protein Binding Cadherin Binding
	Biological Process	Vacuolar Acidification Regulation Of Macroautophagy Toxin Transport Proton Transmembrane Transport	Glutathione Metabolic Process Chloride Transport Signal Transduction Ion Transmembrane Transport Regulation Of Ion Transmembrane Transport Positive Regulation Of Osteoblast Differentiation Regulation Of Cell Cycle Regulation Of Mitochondrial Membrane Potential Platelet Aggregation
Pathways		ROS and RNS production in phagocytes Neutrophil degranulation Insulin receptor recycling Transferrin endocytosis and recycling Ion channel transport
Drugs		Tiludronic acid	Copper Artenimol
Diseases
GWAS		Asthma ( 32296059) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Ulcerative colitis ( 28067908) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)	Adult body size ( 32376654) Asthma ( 31619474) Asthma (childhood onset) ( 31619474) Asthma and major depressive disorder ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 28240269) Inflammatory bowel disease ( 28067908) Mean platelet volume ( 27863252) Ulcerative colitis ( 28067908)
Interacting Genes		7 interacting genes: ABLIM2 CLIC1 CYTH2 HRH1 SEH1L SNX4 ZNF267	24 interacting genes: AKAP9 ALOX5AP ATP5PB ATP6V0A1 ATP6V0C CPT1A DNAJC19 IKBKG LSM1 MEOX2 MYOC NHSL2 NTF4 NUP62 PCSK5 PRDX4 PSMD10 RPLP1 SUMO4 THRA TPRN TRAPPC2 ZNF184 ZNF302
Entrez ID		535	1192
HPRD ID		01886	04188
Ensembl ID		ENSG00000033627	ENSG00000213719
Uniprot IDs		Q53ET5 Q53X12 Q5CZH6 Q93050	O00299 Q53FB0 Q5SRT3
PDB IDs		6WLW 6WM2 6WM3 6WM4	1K0M 1K0N 1K0O 1RK4 3O3T 3P8W 3P90 3QR6 3SWL 3TGZ 3UVH 4IQA 4JZQ 4K0G 4K0N
Enriched GO Terms of Interacting Partners?
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