DGKE and MKS1

		DGKE	MKS1
Description		diacylglycerol kinase epsilon	MKS transition zone complex subunit 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol Plasma Membrane Membrane Integral Component Of Membrane Glutamatergic Synapse	Cytoplasm Centrosome Centriole Cytosol Membrane MKS Complex Ciliary Basal Body
	Molecular Function	NAD+ Kinase Activity Diacylglycerol Kinase Activity ATP Binding Kinase Activity Metal Ion Binding	Protein Binding
	Biological Process	Phosphatidic Acid Biosynthetic Process Phosphatidylinositol Biosynthetic Process Protein Kinase C-activating G Protein-coupled Receptor Signaling Pathway Platelet Activation Intracellular Signal Transduction Diacylglycerol Metabolic Process Lipid Phosphorylation Modulation Of Chemical Synaptic Transmission	Neural Tube Closure Smoothened Signaling Pathway Involved In Regulation Of Secondary Heart Field Cardioblast Proliferation Determination Of Left/right Symmetry Epithelial Structure Maintenance Embryonic Digit Morphogenesis Motile Cilium Assembly Embryonic Skeletal System Development Branching Morphogenesis Of An Epithelial Tube Inner Ear Receptor Cell Stereocilium Organization Cilium Assembly Head Development Cardiac Septum Morphogenesis Regulation Of Canonical Wnt Signaling Pathway Common Bile Duct Development Regulation Of Smoothened Signaling Pathway Involved In Dorsal/ventral Neural Tube Patterning Non-motile Cilium Assembly Embryonic Brain Development Regulation Of Wnt Signaling Pathway, Planar Cell Polarity Pathway
Pathways		Effects of PIP2 hydrolysis	Hedgehog 'off' state Anchoring of the basal body to the plasma membrane
Drugs		alpha-Tocopherol succinate
Diseases
GWAS		Crohn's disease ( 28067908) Early spontaneous preterm birth ( 31194736) Height ( 18391951) Refractive error ( 32231278) Retinal detachment or retinal break ( 31816047)	Eosinophil counts ( 32888494) Eosinophil percentage of white cells ( 32888494) Post bronchodilator FEV1 in COPD ( 26634245) Post bronchodilator FEV1/FVC ratio in COPD ( 26634245)
Interacting Genes		3 interacting genes: HRAS MKS1 MRPL44	7 interacting genes: ABCC3 CACNA1G DDX24 DGKE RNF43 SMG8 TMEM67
Entrez ID		8526	54903
HPRD ID		03259	07900
Ensembl ID		ENSG00000153933	ENSG00000011143
Uniprot IDs		A1L4Q0 P52429	A0A0S2Z5Z2 A0A7I2V2M0 B4DVC5 H0Y2S2 J3KSC6 Q9NXB0
PDB IDs
Enriched GO Terms of Interacting Partners?
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