MKS1 and CACNA1G

		MKS1	CACNA1G
Description		MKS transition zone complex subunit 1	calcium voltage-gated channel subunit alpha1 G
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Centrosome Centriole Cytosol Membrane MKS Complex Ciliary Basal Body	Voltage-gated Sodium Channel Complex Cytoplasm Plasma Membrane Voltage-gated Calcium Channel Complex Neuron Projection Synapse
	Molecular Function	Protein Binding	Voltage-gated Sodium Channel Activity Low Voltage-gated Calcium Channel Activity Voltage-gated Calcium Channel Activity Involved In AV Node Cell Action Potential Voltage-gated Calcium Channel Activity Involved SA Node Cell Action Potential Scaffold Protein Binding
	Biological Process	Neural Tube Closure Smoothened Signaling Pathway Involved In Regulation Of Secondary Heart Field Cardioblast Proliferation Determination Of Left/right Symmetry Epithelial Structure Maintenance Embryonic Digit Morphogenesis Motile Cilium Assembly Embryonic Skeletal System Development Branching Morphogenesis Of An Epithelial Tube Inner Ear Receptor Cell Stereocilium Organization Cilium Assembly Head Development Cardiac Septum Morphogenesis Regulation Of Canonical Wnt Signaling Pathway Common Bile Duct Development Regulation Of Smoothened Signaling Pathway Involved In Dorsal/ventral Neural Tube Patterning Non-motile Cilium Assembly Embryonic Brain Development Regulation Of Wnt Signaling Pathway, Planar Cell Polarity Pathway	Sinoatrial Node Development Chemical Synaptic Transmission Response To Nickel Cation Neuronal Action Potential Regulation Of Ion Transmembrane Transport Sodium Ion Transmembrane Transport Regulation Of Membrane Potential Positive Regulation Of Calcium Ion-dependent Exocytosis Regulation Of Atrial Cardiac Muscle Cell Membrane Depolarization Calcium Ion Import Calcium Ion Transmembrane Transport Cardiac Muscle Cell Action Potential Involved In Contraction Membrane Depolarization During Action Potential SA Node Cell Action Potential AV Node Cell Action Potential SA Node Cell To Atrial Cardiac Muscle Cell Signaling AV Node Cell To Bundle Of His Cell Signaling Membrane Depolarization During AV Node Cell Action Potential Membrane Depolarization During SA Node Cell Action Potential Regulation Of Heart Rate By Cardiac Conduction
Pathways		Hedgehog 'off' state Anchoring of the basal body to the plasma membrane	NCAM1 interactions
Drugs			Ergocalciferol Enflurane Trimethadione Spironolactone Cinnarizine Ethosuximide Verapamil Zonisamide Nifedipine Mibefradil Flunarizine Methsuximide Cannabidiol Trimebutine Benidipine Manidipine Butamben Bioallethrin Bioallethrin Medical Cannabis Nabiximols
Diseases
GWAS		Eosinophil counts ( 32888494) Eosinophil percentage of white cells ( 32888494) Post bronchodilator FEV1 in COPD ( 26634245) Post bronchodilator FEV1/FVC ratio in COPD ( 26634245)	Adventurousness ( 30643258) Alzheimer's disease (cognitive decline) ( 23535033) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) PR interval ( 32439900) Total cholesterol levels ( 30498476)
Interacting Genes		7 interacting genes: ABCC3 CACNA1G DDX24 DGKE RNF43 SMG8 TMEM67	3 interacting genes: MKS1 RANBP9 UBQLN4
Entrez ID		54903	8913
HPRD ID		07900	04961
Ensembl ID		ENSG00000011143	ENSG00000006283
Uniprot IDs		A0A0S2Z5Z2 A0A7I2V2M0 B4DVC5 H0Y2S2 J3KSC6 Q9NXB0	O43497
PDB IDs			6KZO 6KZP
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?