MKS1 and DDX24

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		MKS1	DDX24
Description		MKS transition zone complex subunit 1	DEAD-box helicase 24
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Centrosome Centriole Cytosol Membrane MKS Complex Ciliary Basal Body	Nucleolus Membrane
	Molecular Function	Protein Binding	RNA Binding RNA Helicase Activity ATP Binding ATP Hydrolysis Activity
	Biological Process	Neural Tube Closure Smoothened Signaling Pathway Involved In Regulation Of Secondary Heart Field Cardioblast Proliferation Determination Of Left/right Symmetry Epithelial Structure Maintenance Embryonic Digit Morphogenesis Motile Cilium Assembly Embryonic Skeletal System Development Branching Morphogenesis Of An Epithelial Tube Inner Ear Receptor Cell Stereocilium Organization Cilium Assembly Head Development Cardiac Septum Morphogenesis Regulation Of Canonical Wnt Signaling Pathway Common Bile Duct Development Regulation Of Smoothened Signaling Pathway Involved In Dorsal/ventral Neural Tube Patterning Non-motile Cilium Assembly Embryonic Brain Development Regulation Of Wnt Signaling Pathway, Planar Cell Polarity Pathway	RNA Metabolic Process
Pathways		Hedgehog 'off' state Anchoring of the basal body to the plasma membrane
Drugs
Diseases
GWAS		Eosinophil counts ( 32888494) Eosinophil percentage of white cells ( 32888494) Post bronchodilator FEV1 in COPD ( 26634245) Post bronchodilator FEV1/FVC ratio in COPD ( 26634245)	Oppositional defiant disorder dimensions in attention-deficit hyperactivity disorder ( 26184070) Post bronchodilator FEV1/FVC ratio ( 26634245)
Interacting Genes		7 interacting genes: ABCC3 CACNA1G DDX24 DGKE RNF43 SMG8 TMEM67	34 interacting genes: BCS1L BRCA1 CSNK2A1 EIF3E EP300 FADD GIT1 GLRA2 HSP90AB1 HSPA5 IDO1 ITGB3BP LMNA MDM2 MKS1 MRPL4 NRXN2 PAFAH1B3 PIN1 POLA2 PRF1 PTEN PTPN23 RAE1 SPACA9 SPTAN1 TERF1 TERF2 TERF2IP TMEM9B TPI1 TRDMT1 UBE2I VDAC3
Entrez ID		54903	57062
HPRD ID		07900	05860
Ensembl ID		ENSG00000011143	ENSG00000089737
Uniprot IDs		A0A0S2Z5Z2 A0A7I2V2M0 B4DVC5 H0Y2S2 J3KSC6 Q9NXB0	Q9GZR7
PDB IDs
Enriched GO Terms of Interacting Partners?
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