BRIP1 and SIRT1

  • Number of citations of the paper that reports this interaction (PubMedID 22792074)
  • 25
  • Data Source:
  • BioGRID (enzymatic study)

BRIP1

SIRT1

Description BRCA1 interacting helicase 1 sirtuin 1
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Cerebrospinal AB1-42 levels in normal cognition ( 29274321)
  • Mean corpuscular hemoglobin ( 32888494)
  • Mean corpuscular volume ( 32888494)
  • Ovarian cancer ( 21964575)
  • Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892)
Interacting Genes 14 interacting genes: BLM BRCA1 CREBBP FANCD2 HDAC3 HNRNPC HPN HSD17B14 MRPS23 PATZ1 PECAM1 RPA1 SIRT1 TOPBP1 65 interacting genes: AFP AKT1 AR ARNTL BAZ1B BCL11A BHLHE41 BRIP1 CDK6 CENATAC CHFR CLOCK CSNK2B CTTN E2F1 EP300 ESRRA EZH2 FOS FOXM1 FOXO1 FOXO3 GAPDH H1-5 H3C1 HES1 HEY2 HIC1 HIPK2 HNF4A HOXB9 MAPK8 MPHOSPH8 MYCN NBN NDN NMNAT1 NR1H2 NR1H3 NR1H4 PARP1 PML PPARA PPARG PPARGC1A PRMT1 PSME3 RARA RELA RICTOR RRP8 SATB1 SETD7 SMAD7 SMURF2 SNW1 STK11 STK4 SUMO2 TP53 TP73 TRIM28 UBE2I USP22 VDR
Entrez ID 83990 23411
HPRD ID 05797 08381
Ensembl ID ENSG00000136492 ENSG00000096717
Uniprot IDs Q9BX63 A0A024QZQ1 A8K128 B0QZ35 E9PC49 Q96EB6
PDB IDs 1T15 1T29 3AL3 4I5I 4IF6 4IG9 4KXQ 4ZZH 4ZZI 4ZZJ 5BTR
Enriched GO Terms of Interacting Partners?
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