SIRT1 and FOXO3

  • Number of citations of the paper that reports this interaction (PubMedID 14976264)
  • 1181
  • Data Source:
  • BioGRID (enzymatic study)
  • HPRD (in vivo, two hybrid, in vitro)

SIRT1

FOXO3

Description sirtuin 1 forkhead box O3
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Interacting Genes 65 interacting genes: AFP AKT1 AR ARNTL BAZ1B BCL11A BHLHE41 BRIP1 CDK6 CENATAC CHFR CLOCK CSNK2B CTTN E2F1 EP300 ESRRA EZH2 FOS FOXM1 FOXO1 FOXO3 GAPDH H1-5 H3C1 HES1 HEY2 HIC1 HIPK2 HNF4A HOXB9 MAPK8 MPHOSPH8 MYCN NBN NDN NMNAT1 NR1H2 NR1H3 NR1H4 PARP1 PML PPARA PPARG PPARGC1A PRMT1 PSME3 RARA RELA RICTOR RRP8 SATB1 SETD7 SMAD7 SMURF2 SNW1 STK11 STK4 SUMO2 TP53 TP73 TRIM28 UBE2I USP22 VDR 31 interacting genes: AKT1 ATM BTRC CDK6 CDT1 CHUK EP300 ERBIN ESR1 FOXG1 GPR6 HDAC2 IKBKB MAPK1 MAPK6 MDM2 NR1H2 NR1H3 PRDM13 PTPA SGK1 SIM1 SIRT1 SMAD2 SMAD3 SMAD4 TERT TP53 VDR YWHAG YWHAZ
Entrez ID 23411 2309
HPRD ID 08381 04061
Ensembl ID ENSG00000096717 ENSG00000118689
Uniprot IDs A0A024QZQ1 A8K128 B0QZ35 E9PC49 Q96EB6 O43524
PDB IDs 4I5I 4IF6 4IG9 4KXQ 4ZZH 4ZZI 4ZZJ 5BTR 2K86 2LQH 2LQI 2UZK 6MNL
Enriched GO Terms of Interacting Partners?
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