DOHH and EIF5A

Number of citations of the paper that reports this interaction (PubMedID 28514442)
406

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vitro)

		DOHH	EIF5A
Description		deoxyhypusine hydroxylase	eukaryotic translation initiation factor 5A
Image
GO Annotations	Cellular Component	Cellular_component Cytosol	Nucleus Annulate Lamellae Nuclear Pore Cytoplasm Endoplasmic Reticulum Membrane Cytosol Membrane
	Molecular Function	Iron Ion Binding Protein Binding Oxidoreductase Activity Deoxyhypusine Monooxygenase Activity	RNA Binding Translation Elongation Factor Activity Protein Binding U6 SnRNA Binding Ribosome Binding Protein N-terminus Binding
	Biological Process	Peptidyl-lysine Modification To Peptidyl-hypusine	Translational Elongation Protein Transport Tumor Necrosis Factor-mediated Signaling Pathway Positive Regulation Of Translational Elongation Positive Regulation Of Translational Termination Positive Regulation Of Transcription By RNA Polymerase II MRNA Transport Cellular Response To Virus Positive Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator
Pathways		Hypusine synthesis from eIF5A-lysine	Hypusine synthesis from eIF5A-lysine
Drugs
Diseases
GWAS			Liver enzyme levels (alkaline phosphatase) ( 33972514) Venous thromboembolism ( 31420334)
Interacting Genes		1 interacting genes: EIF5A	17 interacting genes: CRX DHPS DOHH GSC2 LBX1 MEI4 MEOX2 PICK1 REL RPL5 SDCBP STUB1 SUMO2 TGM2 XPO1 XPO4 XRN2
Entrez ID		83475	1984
HPRD ID		14627	02555
Ensembl ID		ENSG00000129932	ENSG00000132507
Uniprot IDs		Q9BU89	P63241
PDB IDs		4D4Z 4D50	1FH4 3CPF 5DLQ
Enriched GO Terms of Interacting Partners?
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