EIF5A and DOHH

Number of citations of the paper that reports this interaction (PubMedID 28514442)
406

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vitro)

		EIF5A	DOHH
Description		eukaryotic translation initiation factor 5A	deoxyhypusine hydroxylase
Image
GO Annotations	Cellular Component	Nucleus Annulate Lamellae Nuclear Pore Cytoplasm Endoplasmic Reticulum Membrane Cytosol Membrane	Cellular_component Cytosol
	Molecular Function	RNA Binding Translation Elongation Factor Activity Protein Binding U6 SnRNA Binding Ribosome Binding Protein N-terminus Binding	Iron Ion Binding Protein Binding Oxidoreductase Activity Deoxyhypusine Monooxygenase Activity
	Biological Process	Translational Elongation Protein Transport Tumor Necrosis Factor-mediated Signaling Pathway Positive Regulation Of Translational Elongation Positive Regulation Of Translational Termination Positive Regulation Of Transcription By RNA Polymerase II MRNA Transport Cellular Response To Virus Positive Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator	Peptidyl-lysine Modification To Peptidyl-hypusine
Pathways		Hypusine synthesis from eIF5A-lysine	Hypusine synthesis from eIF5A-lysine
Drugs
Diseases
GWAS		Liver enzyme levels (alkaline phosphatase) ( 33972514) Venous thromboembolism ( 31420334)
Interacting Genes		17 interacting genes: CRX DHPS DOHH GSC2 LBX1 MEI4 MEOX2 PICK1 REL RPL5 SDCBP STUB1 SUMO2 TGM2 XPO1 XPO4 XRN2	1 interacting genes: EIF5A
Entrez ID		1984	83475
HPRD ID		02555	14627
Ensembl ID		ENSG00000132507	ENSG00000129932
Uniprot IDs		P63241	Q9BU89
PDB IDs		1FH4 3CPF 5DLQ	4D4Z 4D50
Enriched GO Terms of Interacting Partners?
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