EIF5A and DHPS

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid, two hybrid)
HPRD (in vitro, in vivo)

		EIF5A	DHPS
Description		eukaryotic translation initiation factor 5A	deoxyhypusine synthase
Image
GO Annotations	Cellular Component	Nucleus Annulate Lamellae Nuclear Pore Cytoplasm Endoplasmic Reticulum Membrane Cytosol Membrane	Cytoplasm Cytosol
	Molecular Function	RNA Binding Translation Elongation Factor Activity Protein Binding U6 SnRNA Binding Ribosome Binding Protein N-terminus Binding	Protein Binding Deoxyhypusine Synthase Activity Identical Protein Binding
	Biological Process	Translational Elongation Protein Transport Tumor Necrosis Factor-mediated Signaling Pathway Positive Regulation Of Translational Elongation Positive Regulation Of Translational Termination Positive Regulation Of Transcription By RNA Polymerase II MRNA Transport Cellular Response To Virus Positive Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator	Translation Spermidine Metabolic Process Positive Regulation Of Cell Population Proliferation Peptidyl-lysine Modification To Peptidyl-hypusine
Pathways		Hypusine synthesis from eIF5A-lysine	Hypusine synthesis from eIF5A-lysine
Drugs			1-Guanidinium-7-Aminoheptane
Diseases
GWAS		Liver enzyme levels (alkaline phosphatase) ( 33972514) Venous thromboembolism ( 31420334)	Platelet distribution width ( 32888494)
Interacting Genes		17 interacting genes: CRX DHPS DOHH GSC2 LBX1 MEI4 MEOX2 PICK1 REL RPL5 SDCBP STUB1 SUMO2 TGM2 XPO1 XPO4 XRN2	17 interacting genes: BRCA1 EIF5A EIF5A2 LNX1 MEOX2 NIF3L1 NTAQ1 NUDT18 PAX6 PTPRH RAB27B RBP1 REL RPL9 UPF1 VASH1 ZNF138
Entrez ID		1984	1725
HPRD ID		02555	02969
Ensembl ID		ENSG00000132507	ENSG00000095059
Uniprot IDs		P63241	A0A024R7D0 A0A024R7E9 P49366
PDB IDs		1FH4 3CPF 5DLQ	1DHS 1RLZ 1ROZ 1RQD 6P4V 6PGR 6WKZ 6WL6 6XXH 6XXI 6XXJ 6XXK 6XXL 6XXM
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?