EIF5A and MEI4

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		EIF5A	MEI4
Description		eukaryotic translation initiation factor 5A	meiotic double-stranded break formation protein 4
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Annulate Lamellae Nuclear Pore Cytoplasm Endoplasmic Reticulum Membrane Cytosol Membrane	Lateral Element
	Molecular Function	RNA Binding Translation Elongation Factor Activity Protein Binding U6 SnRNA Binding Ribosome Binding Protein N-terminus Binding	Protein Binding
	Biological Process	Translational Elongation Protein Transport Tumor Necrosis Factor-mediated Signaling Pathway Positive Regulation Of Translational Elongation Positive Regulation Of Translational Termination Positive Regulation Of Transcription By RNA Polymerase II MRNA Transport Cellular Response To Virus Positive Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator	DNA Recombination Homologous Chromosome Pairing At Meiosis Spermatogenesis Meiotic DNA Double-strand Break Formation Oogenesis
Pathways		Hypusine synthesis from eIF5A-lysine
Drugs
Diseases
GWAS		Liver enzyme levels (alkaline phosphatase) ( 33972514) Venous thromboembolism ( 31420334)	Brain volume in infants (white matter) ( 28763065) Cadmium levels ( 26025379) Daytime nap ( 33568662) HDL cholesterol levels in HIV infection ( 33109212) Macular thickness ( 30535121)
Interacting Genes		17 interacting genes: CRX DHPS DOHH GSC2 LBX1 MEI4 MEOX2 PICK1 REL RPL5 SDCBP STUB1 SUMO2 TGM2 XPO1 XPO4 XRN2	36 interacting genes: AFMID BAG4 C19orf25 C1orf109 CABP5 CDKN2D CHAF1A CPNE2 CST9L CTTNBP2 DNTT EIF5A FKBP6 GRB2 HSD3B7 IQGAP1 LGALS14 MACO1 METTL21A MLX MTMR9 MYO5B NGB NME7 OSGIN1 PAFAH1B3 PHYHIPL PLEKHA4 POLR1C R3HDM2 TRAPPC2L TRIM59 TSEN15 TSSK3 USHBP1 VPS26C
Entrez ID		1984	101928601
HPRD ID		02555
Ensembl ID		ENSG00000132507	ENSG00000269964
Uniprot IDs		P63241	A8MW99
PDB IDs		1FH4 3CPF 5DLQ
Enriched GO Terms of Interacting Partners?
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