CASP1 and IL1A

  • Number of citations of the paper that reports this interaction (PubMedID 18329368)
  • 329
  • Data Source:
  • HPRD (in vivo)

CASP1

IL1A

Description caspase 1 interleukin 1 alpha
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Hip circumference adjusted for BMI ( 28552196)
  • Dysmenorrheic pain severity ( 29855537)
  • Endometriosis ( 20844546 28537267)
  • Gestational age at birth (child effect) ( 31477735)
  • Interleukin-1-receptor antagonist levels ( 22205395)
  • Neutrophil count ( 32888494)
  • Neutrophil percentage of white cells ( 32888494)
  • Post-term birth ( 31477735)
  • Response to antipsychotic treatment in schizophrenia (working memory) ( 21107309)
Interacting Genes 45 interacting genes: AR ATN1 ATXN3 BCAP31 BCL2L1 BID CARD16 CARD17 CARD8 CASP10 CASP14 CASP8 CAST CDK11B DRD2 EGFR FGF2 HTT HUWE1 IL18 IL1A IL1B IL33 IL37 LMNA MAPT NEDD4 NFE2L2 NLRC4 NLRP1 NOD1 PAK1 PARP1 PLA2G4A PLA2G4B PRKN PSEN1 PSEN2 PYCARD RIPK2 RNF31 SERPINB9 TFAP2A TIRAP VAC14 11 interacting genes: CAPN1 CASP1 HAX1 IL1R1 IL1R2 IL1RAP KPNA6 MEOX2 NDN NFKBIE S100A13
Entrez ID 834 3552
HPRD ID 00977 00988
Ensembl ID ENSG00000137752 ENSG00000115008
Uniprot IDs A8K249 A8K257 P29466 P01583
PDB IDs 1BMQ 1IBC 1ICE 1RWK 1RWM 1RWN 1RWO 1RWP 1RWV 1RWW 1RWX 1SC1 1SC3 1SC4 2FQQ 2H48 2H4W 2H4Y 2H51 2H54 2HBQ 2HBR 2HBY 2HBZ 3D6F 3D6H 3D6M 3E4C 3NS7 5FNA 5MMV 5MTK 6BZ9 6F6R 6KN0 6PZP 6VIE 7KEU 1ITA 2ILA 2KKI 2L5X 5UC6
Enriched GO Terms of Interacting Partners?
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