CASP1 and IL18

  • Number of citations of the paper that reports this interaction (PubMedID 12096920)
  • 87
  • Data Source:
  • BioGRID (enzymatic study)
  • HPRD (in vitro, in vivo)

CASP1

IL18

Description caspase 1 interleukin 18
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Hip circumference adjusted for BMI ( 28552196)
Interacting Genes 45 interacting genes: AR ATN1 ATXN3 BCAP31 BCL2L1 BID CARD16 CARD17 CARD8 CASP10 CASP14 CASP8 CAST CDK11B DRD2 EGFR FGF2 HTT HUWE1 IL18 IL1A IL1B IL33 IL37 LMNA MAPT NEDD4 NFE2L2 NLRC4 NLRP1 NOD1 PAK1 PARP1 PLA2G4A PLA2G4B PRKN PSEN1 PSEN2 PYCARD RIPK2 RNF31 SERPINB9 TFAP2A TIRAP VAC14 9 interacting genes: ADIRF CASK CASP1 CASP3 CASP4 IL18BP IL18R1 IL18RAP IL1RL2
Entrez ID 834 3606
HPRD ID 00977 02976
Ensembl ID ENSG00000137752 ENSG00000150782
Uniprot IDs A8K249 A8K257 P29466 A0A024R3E0 Q14116
PDB IDs 1BMQ 1IBC 1ICE 1RWK 1RWM 1RWN 1RWO 1RWP 1RWV 1RWW 1RWX 1SC1 1SC3 1SC4 2FQQ 2H48 2H4W 2H4Y 2H51 2H54 2HBQ 2HBR 2HBY 2HBZ 3D6F 3D6H 3D6M 3E4C 3NS7 5FNA 5MMV 5MTK 6BZ9 6F6R 6KN0 6PZP 6VIE 7KEU 1J0S 2VXT 3F62 3WO2 3WO3 3WO4 4EEE 4EKX 4HJJ 4R6U 4XFS 4XFT 4XFU
Enriched GO Terms of Interacting Partners?
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