AKAP1 and PTPN21

Number of citations of the paper that reports this interaction (PubMedID 15143158)
52

Data Source:
HPRD (in vivo, in vitro, two hybrid)

		AKAP1	PTPN21
Description		A-kinase anchoring protein 1	protein tyrosine phosphatase non-receptor type 21
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Outer Membrane Cytosol Membrane Integral Component Of Membrane	Cytoplasm Cytoskeleton
	Molecular Function	RNA Binding Protein Binding Protein Kinase A Regulatory Subunit Binding	Protein Tyrosine Phosphatase Activity Protein Binding
	Biological Process	Apoptotic Process Antiviral Innate Immune Response	Protein Dephosphorylation Peptidyl-tyrosine Dephosphorylation
Pathways		Mitochondrial calcium ion transport Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS		Blond vs. brown/black hair color ( 30531825) Crohn's disease ( 26192919) Freckles ( 29895819) Inflammatory bowel disease ( 26192919) Male-pattern baldness ( 27182965)	Prudent dietary pattern ( 28644415) Suicidality in mood disorders ( 33783297) Suicide attempt severity in mood disorders ( 33783297)
Interacting Genes		12 interacting genes: AMY1A CAV1 CFAP91 DYSF MYCBP PPP1CA PRKACA PRKAR1A PRKAR1B PRKAR2A PRKAR2B PTPN21	28 interacting genes: AKAP1 BAG3 BMX CATSPER1 CWC22 ERBB4 FAM214B FBXO17 GOLGA2 KIF1C MAGOHB MOB3C NEK6 NSMF PAK5 PARD6A PIBF1 QARS1 RASD1 SNX18 SRC TEC TRIM14 TTC8 UBASH3B VPS26C YAP1 ZNF497
Entrez ID		8165	11099
HPRD ID		03905	04468
Ensembl ID		ENSG00000121057	ENSG00000070778
Uniprot IDs		A0A140VK05 B4DN86 Q92667	Q16825
PDB IDs
Enriched GO Terms of Interacting Partners?
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