PTPN21 and CWC22

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		PTPN21	CWC22
Description		protein tyrosine phosphatase non-receptor type 21	CWC22 spliceosome associated protein homolog
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytoskeleton	Nucleus Nucleoplasm Spliceosomal Complex Cytosol Nuclear Speck U2-type Precatalytic Spliceosome U2-type Catalytic Step 1 Spliceosome U2-type Catalytic Step 2 Spliceosome Catalytic Step 2 Spliceosome
	Molecular Function	Protein Tyrosine Phosphatase Activity Protein Binding	RNA Binding Protein Binding
	Biological Process	Protein Dephosphorylation Peptidyl-tyrosine Dephosphorylation	MRNA Splicing, Via Spliceosome Regulation Of MRNA Splicing, Via Spliceosome
Pathways			mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Prudent dietary pattern ( 28644415) Suicidality in mood disorders ( 33783297) Suicide attempt severity in mood disorders ( 33783297)	Adult body size ( 32376654) Body mass index ( 28892062) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Schizophrenia ( 30285260)
Interacting Genes		28 interacting genes: AKAP1 BAG3 BMX CATSPER1 CWC22 ERBB4 FAM214B FBXO17 GOLGA2 KIF1C MAGOHB MOB3C NEK6 NSMF PAK5 PARD6A PIBF1 QARS1 RASD1 SNX18 SRC TEC TRIM14 TTC8 UBASH3B VPS26C YAP1 ZNF497	4 interacting genes: EIF4A3 EXOSC8 KLHL2 PTPN21
Entrez ID		11099	57703
HPRD ID		04468	17220
Ensembl ID		ENSG00000070778	ENSG00000163510
Uniprot IDs		Q16825	Q9HCG8
PDB IDs			4C9B 5MQF 5XJC 5YZG 5Z56 5Z57 5Z58 6FF7 6ICZ 6QDV 6YVH 6ZYM 7A5P
Enriched GO Terms of Interacting Partners?
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