EDEM3 and CACYBP

		EDEM3	CACYBP
Description		ER degradation enhancing alpha-mannosidase like protein 3	calcyclin binding protein
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Lumen Membrane Endoplasmic Reticulum Quality Control Compartment	Nucleus Nuclear Envelope Lumen Nucleoplasm Cytosol SCF Ubiquitin Ligase Complex Beta-catenin Destruction Complex Neuron Projection Cell Body Extracellular Exosome
	Molecular Function	Mannosyl-oligosaccharide 1,2-alpha-mannosidase Activity Calcium Ion Binding	Protein Binding Tubulin Binding Protein Domain Specific Binding Ubiquitin Protein Ligase Binding Protein Homodimerization Activity S100 Protein Binding
	Biological Process	Carbohydrate Metabolic Process Protein Glycosylation Response To Unfolded Protein Endoplasmic Reticulum Mannose Trimming Mannose Trimming Involved In Glycoprotein ERAD Pathway	Heart Development Aging Positive Regulation Of DNA Replication Cardiac Muscle Cell Differentiation Response To Growth Hormone Negative Regulation Of Cell Death Cellular Response To Calcium Ion Cellular Response To Leukemia Inhibitory Factor
Pathways		ER Quality Control Compartment (ERQC)
Drugs
Diseases
GWAS		Adult body size ( 32376654) Body size at age 10 ( 32376654) Cerebrospinal fluid immune biomarker levels ( 32066700) Estimated glomerular filtration rate ( 31152163) Liver enzyme levels (alkaline phosphatase) ( 33972514) Metabolite levels ( 23823483) Obesity-related traits ( 23251661) Systemic lupus erythematosus ( 24871463) Urinary albumin-to-creatinine ratio ( 31630189 31511532) Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes		4 interacting genes: CACYBP METTL13 TRA TXNDC5	21 interacting genes: BEX3 CCR2 CD8A EDEM3 ERBB2 FBXO7 HSP90AA1 HSP90B1 MAPK1 NPM1 PEA15 PINX1 PRKCA S100A1 S100A12 S100A6 S100B S100P SIAH1 SIAH2 SKP1
Entrez ID		80267	27101
HPRD ID		10724	07316
Ensembl ID		ENSG00000116406	ENSG00000116161
Uniprot IDs		Q9BZQ6	A0A024R904 Q9HB71
PDB IDs			1X5M 2A25 2A26
Enriched GO Terms of Interacting Partners?
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