EDEM3 and METTL13

		EDEM3	METTL13
Description		ER degradation enhancing alpha-mannosidase like protein 3	methyltransferase 13, eEF1A lysine and N-terminal methyltransferase
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Lumen Membrane Endoplasmic Reticulum Quality Control Compartment	Nucleus Cytoplasm Mitochondrion
	Molecular Function	Mannosyl-oligosaccharide 1,2-alpha-mannosidase Activity Calcium Ion Binding	Protein Binding Methyltransferase Activity
	Biological Process	Carbohydrate Metabolic Process Protein Glycosylation Response To Unfolded Protein Endoplasmic Reticulum Mannose Trimming Mannose Trimming Involved In Glycoprotein ERAD Pathway	Negative Regulation Of Transcription By RNA Polymerase II Methylation Negative Regulation Of Cell Cycle G1/S Phase Transition
Pathways		ER Quality Control Compartment (ERQC)
Drugs
Diseases
GWAS		Adult body size ( 32376654) Body size at age 10 ( 32376654) Cerebrospinal fluid immune biomarker levels ( 32066700) Estimated glomerular filtration rate ( 31152163) Liver enzyme levels (alkaline phosphatase) ( 33972514) Metabolite levels ( 23823483) Obesity-related traits ( 23251661) Systemic lupus erythematosus ( 24871463) Urinary albumin-to-creatinine ratio ( 31630189 31511532) Waist circumference adjusted for body mass index ( 34021172)	Cognitive decline rate in late mild cognitive impairment ( 26252872) Diffusing capacity of carbon monoxide ( 30694715) Platelet distribution width ( 32888494)
Interacting Genes		4 interacting genes: CACYBP METTL13 TRA TXNDC5	5 interacting genes: EDEM3 SNRPA THAP1 TRAF2 VPS52
Entrez ID		80267	51603
HPRD ID		10724	13821
Ensembl ID		ENSG00000116406	ENSG00000010165
Uniprot IDs		Q9BZQ6	C4B4C6 Q8N6R0
PDB IDs			5WCJ
Enriched GO Terms of Interacting Partners?
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