CACYBP and EDEM3

		CACYBP	EDEM3
Description		calcyclin binding protein	ER degradation enhancing alpha-mannosidase like protein 3
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nuclear Envelope Lumen Nucleoplasm Cytosol SCF Ubiquitin Ligase Complex Beta-catenin Destruction Complex Neuron Projection Cell Body Extracellular Exosome	Endoplasmic Reticulum Lumen Membrane Endoplasmic Reticulum Quality Control Compartment
	Molecular Function	Protein Binding Tubulin Binding Protein Domain Specific Binding Ubiquitin Protein Ligase Binding Protein Homodimerization Activity S100 Protein Binding	Mannosyl-oligosaccharide 1,2-alpha-mannosidase Activity Calcium Ion Binding
	Biological Process	Heart Development Aging Positive Regulation Of DNA Replication Cardiac Muscle Cell Differentiation Response To Growth Hormone Negative Regulation Of Cell Death Cellular Response To Calcium Ion Cellular Response To Leukemia Inhibitory Factor	Carbohydrate Metabolic Process Protein Glycosylation Response To Unfolded Protein Endoplasmic Reticulum Mannose Trimming Mannose Trimming Involved In Glycoprotein ERAD Pathway
Pathways			ER Quality Control Compartment (ERQC)
Drugs
Diseases
GWAS			Adult body size ( 32376654) Body size at age 10 ( 32376654) Cerebrospinal fluid immune biomarker levels ( 32066700) Estimated glomerular filtration rate ( 31152163) Liver enzyme levels (alkaline phosphatase) ( 33972514) Metabolite levels ( 23823483) Obesity-related traits ( 23251661) Systemic lupus erythematosus ( 24871463) Urinary albumin-to-creatinine ratio ( 31630189 31511532) Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes		21 interacting genes: BEX3 CCR2 CD8A EDEM3 ERBB2 FBXO7 HSP90AA1 HSP90B1 MAPK1 NPM1 PEA15 PINX1 PRKCA S100A1 S100A12 S100A6 S100B S100P SIAH1 SIAH2 SKP1	4 interacting genes: CACYBP METTL13 TRA TXNDC5
Entrez ID		27101	80267
HPRD ID		07316	10724
Ensembl ID		ENSG00000116161	ENSG00000116406
Uniprot IDs		A0A024R904 Q9HB71	Q9BZQ6
PDB IDs		1X5M 2A25 2A26
Enriched GO Terms of Interacting Partners?
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