ARHGEF5 and FKBP8

  • Number of citations of the paper that reports this interaction (PubMedID 21988832)
  • 87
  • Data Source:
  • BioGRID (two hybrid)

ARHGEF5

FKBP8

Description Rho guanine nucleotide exchange factor 5 FKBP prolyl isomerase 8
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Breast cancer ( 23535729)
  • Breast cancer, ovarian cancer or prostate cancer (pleiotropy) ( 27432226)
  • Gut microbiota relative abundance (Parabacteroides) ( 33208821)
  • Post bronchodilator FEV1/FVC ratio ( 26634245)
  • Plasma parathyroid hormone levels ( 30134803)
  • Urinary potassium excretion ( 31409800)
Interacting Genes 29 interacting genes: APP ATP13A1 CALCOCO2 CCNE1 CHPF COG6 EFHC2 EPM2AIP1 FKBP8 HSF2BP HSPBAP1 LMO2 LRATD1 MB21D2 MID2 NR4A1 PICK1 PLCG1 PLEKHG4 POLR1C RHOA SEPHS2 SLAIN1 SLU7 TBC1D13 TCF4 TRIM27 TRIM54 ZRANB1 50 interacting genes: ANKMY2 ARHGEF5 ARL13B ATP13A2 BCL2 BCL2L1 BNIPL CD79A CIDEB CLCN1 CXCR2 CYB561 CYBRD1 EBP EGFR ELOVL4 ERBB2 ERGIC3 FAM174A FGF14 GPR37 JAGN1 MAPK14 MFSD14B MTOR OGT PEX12 PLN PPP3CA PSMC1 PSMD2 RETREG3 RHBDD2 RHEB SCN3B SHANK3 SLC10A6 SLC35A5 SLC35B1 SMO TERF1 TMEM14B TMEM254 TMEM31 TMEM43 TMEM45B TMEM80 TMX1 VHL ZFPL1
Entrez ID 7984 23770
HPRD ID 02932 05327
Ensembl ID ENSG00000050327 ENSG00000105701
Uniprot IDs Q12774 A0A024R7P2 B2R8G6 Q14318
PDB IDs 2AWG 2D9F 2F2D 2MF9 3EY6 5MGX
Enriched GO Terms of Interacting Partners?
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