ARHGEF5 and EFHC2

  • Number of citations of the paper that reports this interaction (PubMedID 25416956)
  • 484
  • Data Source:
  • BioGRID (two hybrid, two hybrid, two hybrid)

ARHGEF5

EFHC2

Description Rho guanine nucleotide exchange factor 5 EF-hand domain containing 2
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Breast cancer ( 23535729)
  • Breast cancer, ovarian cancer or prostate cancer (pleiotropy) ( 27432226)
  • Gut microbiota relative abundance (Parabacteroides) ( 33208821)
  • Post bronchodilator FEV1/FVC ratio ( 26634245)
  • Body mass index and diastolic blood pressure (bivariate analysis) ( 33539483)
  • Glaucoma (primary open-angle) ( 33627673)
  • Mean arterial pressure ( 29403010)
Interacting Genes 29 interacting genes: APP ATP13A1 CALCOCO2 CCNE1 CHPF COG6 EFHC2 EPM2AIP1 FKBP8 HSF2BP HSPBAP1 LMO2 LRATD1 MB21D2 MID2 NR4A1 PICK1 PLCG1 PLEKHG4 POLR1C RHOA SEPHS2 SLAIN1 SLU7 TBC1D13 TCF4 TRIM27 TRIM54 ZRANB1 100 interacting genes: - AASDHPPT ARHGEF5 ARMC7 CABP2 CACNB4 CARD9 CCDC102B CCDC120 CCDC13 CCDC57 CCHCR1 CCNG2 CDKN2A CLIC3 COPE CPNE2 CPNE7 CYFIP1 DCLK1 DDX6 DGCR6 DRC7 EDC3 EFHC1 EGLN3 EMD ENKD1 ESRRG EXOC8 EXOSC5 FAM107A FAM124B FAM214B FAM221B FBXL19 GEM GLYCTK GOLGA1 GPKOW GRB2 GYS1 HDAC4 HGS HNRNPLL INPP5J JAKMIP2 KANK2 KCTD7 KIF9 L3MBTL2 LMNB2 LMO2 LNX1 LONRF1 MAGOHB MAPK9 MID2 MISP MYLIP MYO5B NCDN NCK2 NDOR1 NEK6 NFKBID NME7 NR3C1 PBLD PHF1 PIBF1 PICK1 PLOD3 POLR1C PRPF18 PTK6 QARS1 RAD51D RCOR3 RECK RHOBTB3 RUNX1T1 SNRNP25 SOGA1 SPATA18 SPG21 STK16 TBC1D1 TBC1D22B TEKT4 TRIM42 TRIM50 TSSK3 TUBGCP4 TXK U2AF1 USP2 ZBTB16 ZFHX3 ZZZ3
Entrez ID 7984 80258
HPRD ID 02932 06540
Ensembl ID ENSG00000050327 ENSG00000183690
Uniprot IDs Q12774 Q5JST6
PDB IDs 2Z13 2Z14
Enriched GO Terms of Interacting Partners?
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