FKBP8 and CYBRD1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		FKBP8	CYBRD1
Description		FKBP prolyl isomerase 8	cytochrome b reductase 1
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GO Annotations	Cellular Component	Mitochondrion Endoplasmic Reticulum Cytosol Membrane Integral Component Of Endoplasmic Reticulum Membrane Mitochondrial Membrane Protein-containing Complex	Lysosomal Membrane Plasma Membrane Integral Component Of Membrane Apical Plasma Membrane Brush Border Membrane Extracellular Exosome
	Molecular Function	Peptidyl-prolyl Cis-trans Isomerase Activity Protein Binding Identical Protein Binding Protein Folding Chaperone Metal Ion Binding Disordered Domain Specific Binding	Protein Binding Oxidoreductase Activity Oxidoreductase Activity, Acting On Metal Ions Identical Protein Binding Metal Ion Binding Transmembrane Ascorbate Ferrireductase Activity Transmembrane Monodehydroascorbate Reductase Activity
	Biological Process	Protein Peptidyl-prolyl Isomerization Cell Fate Specification Negative Regulation Of Protein Phosphorylation Protein Folding Apoptotic Process Smoothened Signaling Pathway Regulation Of Gene Expression Dorsal/ventral Neural Tube Patterning Positive Regulation Of BMP Signaling Pathway Multicellular Organism Growth Intracellular Signal Transduction Camera-type Eye Development Negative Regulation Of Apoptotic Process	Cellular Iron Ion Homeostasis Response To Iron Ion Reductive Iron Assimilation Iron Ion Homeostasis Transmembrane Transport Ascorbate Homeostasis
Pathways		Ub-specific processing proteases	Iron uptake and transport
Drugs
Diseases
GWAS		Plasma parathyroid hormone levels ( 30134803) Urinary potassium excretion ( 31409800)	Body fat distribution (arm fat ratio) ( 30664634) Heel bone mineral density ( 30598549) Hip circumference adjusted for BMI ( 34021172) Pulse pressure ( 30224653) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		50 interacting genes: ANKMY2 ARHGEF5 ARL13B ATP13A2 BCL2 BCL2L1 BNIPL CD79A CIDEB CLCN1 CXCR2 CYB561 CYBRD1 EBP EGFR ELOVL4 ERBB2 ERGIC3 FAM174A FGF14 GPR37 JAGN1 MAPK14 MFSD14B MTOR OGT PEX12 PLN PPP3CA PSMC1 PSMD2 RETREG3 RHBDD2 RHEB SCN3B SHANK3 SLC10A6 SLC35A5 SLC35B1 SMO TERF1 TMEM14B TMEM254 TMEM31 TMEM43 TMEM45B TMEM80 TMX1 VHL ZFPL1	20 interacting genes: CREB3 FKBP8 GIMAP5 GOSR2 HMOX1 LMNA LPAR3 NEDD4L PLP2 RABAC1 SEC22A SERP1 SERP2 STX4 STX7 TMEM120A TMEM65 VAPA VAPB ZFPL1
Entrez ID		23770	79901
HPRD ID		05327	05764
Ensembl ID		ENSG00000105701	ENSG00000071967
Uniprot IDs		A0A024R7P2 B2R8G6 Q14318	Q53TN4
PDB IDs		2AWG 2D9F 2F2D 2MF9 3EY6 5MGX	5ZLE 5ZLG
Enriched GO Terms of Interacting Partners?
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