TRPC5 and STMN2

Number of citations of the paper that reports this interaction (PubMedID 12858178)
117

Data Source:
HPRD (in vivo, two hybrid)

		TRPC5	STMN2
Description		transient receptor potential cation channel subfamily C member 5	stathmin 2
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane Dendrite Growth Cone Cation Channel Complex Calcium Channel Complex Neuronal Cell Body Membrane Raft	Cytoplasm Endosome Golgi Apparatus Cytosol Membrane Lamellipodium Growth Cone Neuron Projection Neuronal Cell Body Perinuclear Region Of Cytoplasm
	Molecular Function	Actin Binding Calcium Channel Activity Protein Binding Store-operated Calcium Channel Activity Clathrin Binding Actinin Binding ATPase Binding Inositol 1,4,5 Trisphosphate Binding	Protein Binding Tubulin Binding Calcium-dependent Protein Binding
	Biological Process	Calcium Ion Transport Manganese Ion Transport Positive Regulation Of Cytosolic Calcium Ion Concentration Nervous System Development Positive Regulation Of Cell Population Proliferation Positive Regulation Of Peptidyl-threonine Phosphorylation Neuron Differentiation Positive Regulation Of Neuron Differentiation Positive Regulation Of Axon Extension Negative Regulation Of Dendrite Morphogenesis Neuron Apoptotic Process Regulation Of Cytosolic Calcium Ion Concentration Calcium Ion Transmembrane Transport Phosphatidylserine Exposure On Apoptotic Cell Surface Regulation Of Membrane Hyperpolarization	Microtubule Depolymerization Negative Regulation Of Microtubule Depolymerization Positive Regulation Of Neuron Projection Development Negative Regulation Of Neuron Projection Development Regulation Of Microtubule Polymerization Or Depolymerization Negative Regulation Of Microtubule Polymerization Positive Regulation Of Microtubule Depolymerization Neuron Projection Development Cellular Response To Nerve Growth Factor Stimulus
Pathways		TRP channels Role of second messengers in netrin-1 signaling	RND1 GTPase cycle
Drugs
Diseases
GWAS		Smoking behavior ( 19247474)	Creutzfeldt-Jakob disease ( 19081515) Frontotemporal dementia with GRN mutation (age at onset) ( 29724592) Metabolite levels ( 23823483) Metastatic colorectal cancer survival in treatment with chemotherapy plus biologics ( 32958699) Response to serotonin reuptake inhibitors in major depressive disorder ( 25897834)
Interacting Genes		10 interacting genes: DRD2 ENKUR ITPR3 MX1 PLS3 SLC9A3R1 STMN2 STMN3 TRPC1 TRPC4	28 interacting genes: CCDC85A CCHCR1 CDC42 CDK1 CEP70 CTNNA3 EEF1A1 ERBB2 FAM90A1 FANCC GPRASP1 GPRASP2 MAPK10 MAPK3 MBD3 NGFR NTAQ1 PRKACA PSMB1 PSMC1 RGS20 RGS6 SESTD1 TEX11 TFCP2 TRPC5 TXLNA UBE2I
Entrez ID		7224	11075
HPRD ID		02273	09003
Ensembl ID		ENSG00000072315	ENSG00000104435
Uniprot IDs		Q9UL62	Q93045
PDB IDs		6YSN
Enriched GO Terms of Interacting Partners?
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