STMN2 and SESTD1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		STMN2	SESTD1
Description		stathmin 2	SEC14 and spectrin domain containing 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endosome Golgi Apparatus Cytosol Membrane Lamellipodium Growth Cone Neuron Projection Neuronal Cell Body Perinuclear Region Of Cytoplasm	Intermediate Filament Cytoskeleton
	Molecular Function	Protein Binding Tubulin Binding Calcium-dependent Protein Binding	Phosphatidylserine Binding Protein Binding 1-phosphatidylinositol Binding Phosphatidylinositol-4,5-bisphosphate Binding Phosphatidylinositol-5-phosphate Binding Phosphatidylcholine Binding Phosphatidylinositol-3-phosphate Binding Phosphatidylinositol-3,4-bisphosphate Binding Phosphatidylinositol-4-phosphate Binding Phosphatidic Acid Binding Phosphatidylinositol-3,5-bisphosphate Binding
	Biological Process	Microtubule Depolymerization Negative Regulation Of Microtubule Depolymerization Positive Regulation Of Neuron Projection Development Negative Regulation Of Neuron Projection Development Regulation Of Microtubule Polymerization Or Depolymerization Negative Regulation Of Microtubule Polymerization Positive Regulation Of Microtubule Depolymerization Neuron Projection Development Cellular Response To Nerve Growth Factor Stimulus	Negative Regulation Of Calcium Ion Transmembrane Transport Via High Voltage-gated Calcium Channel
Pathways		RND1 GTPase cycle
Drugs
Diseases
GWAS		Creutzfeldt-Jakob disease ( 19081515) Frontotemporal dementia with GRN mutation (age at onset) ( 29724592) Metabolite levels ( 23823483) Metastatic colorectal cancer survival in treatment with chemotherapy plus biologics ( 32958699) Response to serotonin reuptake inhibitors in major depressive disorder ( 25897834)	Late-onset Alzheimer's disease ( 27770636) Objective response to lithium treatment ( 26503763) Optic disc size ( 31809533) Presence of antiphospholipid antibodies ( 23509613) Refractive error ( 32231278) Serum uric acid levels ( 29559957)
Interacting Genes		28 interacting genes: CCDC85A CCHCR1 CDC42 CDK1 CEP70 CTNNA3 EEF1A1 ERBB2 FAM90A1 FANCC GPRASP1 GPRASP2 MAPK10 MAPK3 MBD3 NGFR NTAQ1 PRKACA PSMB1 PSMC1 RGS20 RGS6 SESTD1 TEX11 TFCP2 TRPC5 TXLNA UBE2I	10 interacting genes: CBX8 DACT3 GPS2 HSF4 IQCB1 RABGEF1 STMN1 STMN2 TEAD4 ZNF830
Entrez ID		11075	91404
HPRD ID		09003	11549
Ensembl ID		ENSG00000104435	ENSG00000187231
Uniprot IDs		Q93045	B3KTX3 Q86VW0
PDB IDs
Enriched GO Terms of Interacting Partners?
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